Optimizing P2Y12 receptor inhibition in patients with acute coronary syndrome on the basis of platelet function testing: impact of prasugrel and high-dose ... Patients with ACS who were pre-treated with clopidogrel and undergoing successful PCI were enrolled in a single-center, prospective registry....
according to the type of stent (PtCr-EES versus BP-BES) and prasugrel maintenance dose (5 mg versus 10 mg), to demonstrate non-inferiority of PtCr-EES relative to BP-BES or the reduced prasugrel dose relative to conventional dose in an Asian all-comers PCI population presenting with ACS....
Ok! (HealthDay)—For patients presenting with acute coronary syndrome (ACS) who undergo percutaneous coronary intervention (PCI), a postrandomization subgroup analysis suggests that a prasugrel-based strategy is superior to a ticagrelor-based strategy, according to a study published online June 30 in...
(HealthDay)—For elderly or low-weight patients with acute coronary syndrome (ACS), a reduced dose of prasugrel is efficacious compared with ticagrelor, according to a study published online July 21 in the Annals of Internal Medicine.
A lower dose of prasugrel in patients aged ≥75 years and those weighing <60 kg may help to minimize the bleeding risk, although more data are needed to establish this; prasugrel is contraindicated in patients with a history of stroke or transient ischaemic attack. Thus, prasugrel provides a ...
The goal of this study was to determine whether there is a relationship between aspirin dose and the potent antiplatelet agent prasugrel in the TRITON–TIM... Kohli P; Udell JA; Murphy SA; Cannon CP; Antman EM; Braunwald E; Wiviott SD - 《Journal of the American College of Cardiology》 ...
The trial compared two types of patients with ACS , those with ST-segment elevation MI (STEMI) and those with non-STEMI orunstable angina; two types of antiplatelet therapy, ticagrelor and prasugrel; and two treatment strategies, an antiplatelet loading dose before or after angiography. ...
in the management of ACS because many cardiovascular events occur within hours of initial presentation, in a trial of 4033 NSTEMI patients, no clear benefit was observed when Effient loading dose was administered prior to diagnostic coronary angiography compared to at the time of PCI; however, ...
Prasugrel demonstrated superiority to double-dose clopidogrel in overcoming HTPR and reducing platelet activity. Intensifying antiplatelet therapy in both ACS and stable angina pectoris (SAP) patients exhibiting HTPR prior to PCI was well tolerated. 展开 关键词: Antiplatelet therapy clopidogrel prasugrel ...
Overdose/Missed Dose Reviews (8) Uses What is prasugrel used for? Prasugrel is commonly used to lower the risk of having a heart attack or other serious problem with your heart or blood vessels in any of the following situations. You have previously had a heart attack ...