on caudate neurones A direct “post-synaptic” and “dopamine-like” effect of amphetamine on caudate neuronesA direct “post-synaptic” and “dopamine-like” effect of amphetamine on caudate neuronesA technique was developed combining multibarrelled glass microelectrode recordings with local super...
In selective serotonin reuptake inhibitors (SSRIs), what is the benefit of increasing the level of serotonin in the synapses, while what is wanted is to increase the amount of serotonin released by the pre-synaptic neuron to the post-synaptic neuron?
W. (1984). Post-synaptic inhibition of bulbarinspiratory neurones in the cat. Journal of Physiokogy 348, 67-87.Ballantyne, D, Richter, DW (1984) Postsynaptic inhibition of bulbar inspiratory neurones in the cat. J. Physiol. (Lond.) 348: pp. 67...
39 NAS GABAAR PAMs have pharmacological profiles and binding sites distinct from benzodiazepines,40,41 with the ability to modulate the activity of both synaptic and extrasynaptic GABAARs.39,42 Therefore, we performed a phase 3, double-blind, randomized, placebo-controlled clinical trial comparing ...
EPSP is a post-synaptic potential that makes a neuron more likely to fire an action potential. This temporary depolarization of post-synaptic membrane potential, caused by the flow of positively charged neurotransmit- ters into the postsynaptic cell, is a result of opening ligand-gated ...
Postganglionic sympathetic neurones supplying skeletal muscle and skin can be activated from the preganglionic site via cholinergic nicotinic, muscarinic and non-cholinergic synaptic mechanisms. The experiments described in this paper were designed in order to show that postganglionic vasoconstrictor neuro...
We hypothesized that neuroinflammatory events could alter neural and synaptic plasticity in the thalamus, which caused functional changes in the output brain regions, such as anterior cingulate cortex and prefrontal cortex, and eventually led to anxiety and depression, since transcranial direct current ...
We observed pervasive, neuron-type-specific changes in gene expression, many of which are controlled by the developmental upregulation of the conserved heterochronic microRNA LIN-4 and the subsequent promotion of a mature neuronal transcriptional program through the repression of its target, the ...
The development and anatomical projection of most lineages remains largely unknown; ascertaining this knowledge and using it to generate an accurate map of Drosophila brain circuitry at the level of neuron populations (“macro-circuitry”) is an important project followed by us and others over the ...
(1) monosynaptic input from excitatory calretinin cells (eCRs), (2) polysynaptic circuits that include an eCR, or (3) a di-synaptic circuit in which an iCR forms an axoaxonic syn- apse on a primary afferent central terminal that is itself presynaptic to the recorded neuron (Fig. 11a)...