3,505 patients (11.9%) had ANA tested multiple times (range: 2-25 times). In 31% of the patients having multiple ANA, the result was repeatedly negative; 41% stayed repeatedly positive; 16% of patients had an initial negative ANA and a subsequent positive; 12% had an initial positive ...
The study found ANA and anti-dsDNA in AVV patients were not rare, ANA-positive AAV patients had severer kidney damage and more chronic renal histopathological changes compared to ANA-negative AAV patients. Renal biopsy is strongly recommended for differential diagnosis in such cases....
negative AMA negative ASMA negative ANA Antinuclear antibody, AC-4 Anti cell-4 pattern, ENA Extractable nuclear antigen, RNP Ribonucleoprotein, Sm Smith, p-ANCA Perinuclear anti-neutrophil cytoplasmic antibodies, c-ANCA Antineutrophil cytoplasmic antibodies, dsDNA Double stranded DNA, AMA Antimitochondrial...
Fig. 1.IFA detectsFcaGHV1antibodies in infected cats. The left axis indicates therecombinant proteinantigen that was transfected into each set of cells. SPF-naive cat serum was used as a negative control in all assays. Fluorescence in the second column (anti-HA) indicates cells expressing the...
Autoimmune workup revealedpositive ANA 1:640 (nucleolar) and 1:160 (speckled), positive U1RNP, and RNA polymerase III with negativeSSA/SSB/dsDNA and Scl-70 Ab. Following elective implant removal after nationwide recall for heightened cancer risk, many of her symptoms spontaneously resolved. The ...
We conclude that anti-dsDNA are common in ANA-positive type 1 autoimmune hepatitis. HLA DR4 is associated with their production, and seropositivity by ELISA characterizes patients who have a poorer immediate response to corticosteroid treatment. Anti-ssDNA are common but they do not have important ...
Interestingly, DC were also significantly elevated in SLE with high SLEDAI, anti-dsDNA, ANA and ESR. NGF serum concentrations did not differ between SLE and HC.ConclusionsOur data for the first time demonstrate differential NGF receptor expression on an extensive panel of peripheral blood leukocytes...
Both speckled antinuclear antibody (ANA) and anti-U1 ribonucleoprotein (RNP) antibody were positive, but anti-double-stranded DNA (dsDNA) antibody and anti-Smith (Sm) antibody were negative, while complement levels were normal. Renal biopsy revealed membranous glomerulonephritis (MGN) with diffuse ...
Of the 218 AAV patients, 109 (50.0%) were positive for ANA, 45 (20.6%) were positive for anti-dsDNA, and 43 (19.7%) were positive for both. The AAV patients with ANA had severer kidney damage and more chronic renal histopathological changes compared to those who were negative for ANA....
Laboratory testing revealed low serum complement levels and positive titers for ANA, SSA, and dsDNA; AQP4-IgG was positive at a titer of > 1:100,000. Myelin oligodendrocyte glycoprotein (MOG) and antiphospholipid antibodies were negative. Skin biopsy demonstrated leukocytoclastic vasculitis. MRI ...