Studies of multifactorial inheritance in man have ignored nonadditive gene action or attributed it entirely to dominance. Reanalyses of dermatoglyphic data on monozygotic and dizygotic twins, siblings and parents and offspring suggest ...
Altered Inheritance: CRISPR and the Ethics of Human Genome Editing (Harvard Univ. Press, 2019). Book MATH Google Scholar Bavelier, D. et al. Rethinking human enhancement as collective welfarism. Nat. Hum. Behav. 3, 204–206 (2019). Article PubMed PubMed Central Google Scholar Lander, E...
Polygenic genome editing in human embryos and germ cells is predicted to become feasible in the next three decades. Several recent books and academic papers have outlined the ethical concerns raised by germline genome editing and the opportunities that i
J. J. Co-heritability: its relation to correlated response, linkage, and pleiotropy in cases of polygenic inheritance. Euphytica 28, 601–608 (1979). Article Google Scholar Pirinen, M., Donnelly, P. & Spencer, C. C. A. Including known covariates can reduce power to detect genetic ...
Multiple Allele, Sex-linked, Polygenic Inheritance quiz for 10th grade students. Find other quizzes for Biology and more on Quizizz for free!
In polygenic inheritance, Punnett square would show greater offspring variations from a test cross, and therefore, would not be as straightforward as it is in a monogenic inheritance.Monogenic Trait vs. Polygenic Trait As mentioned earlier, a monogenic trait is a trait that results when a single...
7,8 We have demonstrated that the SCAD PRS is significantly elevated in individuals with SCAD relative to healthy controls.8 Familial clustering of SCAD has been reported multiple times9-12 but often without a clear mendelian inheritance pattern. However, small cohort and/or pedigree size have ...
inheritance in some families indicates a Y allele on LG13, which would support the presence of an XYW system; however, occasional apparently sex reversed individuals make the conclusion that both W and Y alleles are present at LG13 tentative. The locus on LG13 represents a novel association wi...
processing, such as working memory, selective attention, and executive functions, exhibit polygenic inheritance24. The above literature indicates a polygenic architecture underlying auditory-cognitive processes involved in SIN deficits. The present GWAS evaluated the polygenic architecture underlying SIN ...
S. The inheritance of liability to certain diseases, estimated from the incidence among relatives. Ann. Hum. Genet. 29, 51–76 (1965). Google Scholar Reich, T., James, J. W. & Morris, C. A. The use of multiple thresholds in determining the mode of transmission of semi-continuous ...