Polygenic inheritance ("poly-" many; "-genic" gene) refers to genetic inheritance patterns which are controlled by more than one gene. Because multiple genes control the trait, or character, that is being obser
Nevertheless, this scandal highlights the relatively advanced (although still error-prone) status of gene editing technologies and the need for a translational pathway if this technology is to be used in humans6,7,8. The birth of Lulu and Nana was followed by the birth of Aurea—the first ...
Mitosis, Meiosis, and Inheritance Multifactorial Inheritance and Genetic Disease Non-nuclear Genes and Their Inheritance Polygenic Inheritance and Gene Mapping Sex Chromosomes and Sex Determination Sex Determination in Honeybees Test Crosses Methods for Studying Inheritance Patterns C. elegans: Mo...
(although still error-prone) status of gene editing technologies and the need for a translational pathway if this technology is to be used in humans6,7,8. The birth of Lulu and Nana was followed by the birth of Aurea—the first child born via embryo screening using polygenic scores (ESP...
What are the traits in humans that are determined by multiple alleles? Define a dominant trait. What is a recessive allele? What is natural selection, and does it act on genotype or phenotype? What is the phenotype of a homozygous dominant individual? What is the genetic inheritance of the ...
inheritance patterns; however, interaction of multiple sex alleles may produce skewed sex ratios or non-viable genotypes. In cichlids and other fish species, co-segregation of both Y and W alleles in families produces female-biased sex ratios [18,22,30], and in pygmy mice with an XYW system...
inheritance patterns; however, interaction of multiple sex alleles may produce skewed sex ratios or non-viable genotypes. In cichlids and other fish species, co-segregation of both Y and W alleles in families produces female-biased sex ratios [18,22,30], and in pygmy mice with an XYW system...
Humans are diploid organisms. This means that the somatic cells, or body cells, of a human contain two copies of every chromosome. The result is that most people have two copies of almost every gene. There are some exceptions ...
Non-contact anterior cruciate ligament (ACL) rupture is a common serious orthopaedic disease in humans and dogs. Familial risk has been recognized in both species but interactions between genetic effects and environmental risk are not understood. We investigated ACL rupture heritability, genetic architect...
unrelated individuals. In this paper we explore these observations from the perspective of genetic similarity and DNA inheritance—see Fig.1. We study both realized phenotypes as well as genotypes, in particular in the form of polygenic scores (PGS). PGS are typically linear functions of thousands...