We review the field from the perspective of poly(A) tail length. Length control is important because (1) poly(A) tail shortening from a defined starting point acts as a timer of mRNA stability, (2) changes in poly(A) tail length are used for the purpose of translational regulation, and...
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Approximately 50% of the m6A is located in the poly(A) tail of the actively expressed VSG transcripts. m6A residues are removed from the VSG poly(A) tail before deadenylation and mRNA degradation. Computational analysis revealed an association between m6A in the poly(A) tail and a 16-mer ...
we show that poly(A) tail length and internal non-A residues are highly dynamic during the human OET, using poly(A)-inclusive RNA isoform sequencing (PAIso-seq). Unexpectedly, maternal
While poly(A) tail length influences mRNA translation efficiency during the oocyte-to-embryo transition (OET), molecular mechanisms regulating maternal RNA poly(A) tail length are not fully understood. In this study, we identified MARTRE, a previously uncharacterized protein family (MARTRE1-MARTRE6...
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For the purpose of developing poly(3-hexylthiophene) (P3HT) based copolymers with deep-lying highest occupied molecular orbital (HOMO) levels for polymer s... Rudenko, Andrey E.Khlyabich, Petr P.Thompson, Barry C. - 《Journal of Polymer Science Part A Polymer Chemistry》 被引量: 0发表: ...
A number of polysulfides have been prepared by reacting alkenes or dialkenes directly with molten sulfur.The general objective has been to prepare systems with a large proportion of sulfur (over 90%) and these compositions are often termed ‘modified sulfur’. The purpose is to obtain a stable...
Therefore, PMMA was found to be a good and compatible polymer for this purpose. This was attributed to its mechanical strength, compatibility, and optical clarity[27]. Solar and nanotechnology applications Due to the wider application of nanocomposites in the field of nanotechnology, many researchers...
The polyadenosine tail (poly[A]-tail) is a universal modification of eukaryotic messenger RNAs (mRNAs) and non-coding RNAs (ncRNAs). In budding yeast, Pap1-synthesized mRNA poly(A) tails enhance export and translation, whereas Trf4/5-mediated polyadenyla