Heidmann, Role of poly(A) tail length in Alu retrotransposition, Genomics 86 (2005) 378-381.Dewannieux M, Heidmann T. Role of poly(A) tail length in Alu retrotransposition. Genomics. 2005;86(3):378-81.Dewannieux M, Heidmann T (2005) Role of poly(A) tail length in Alu retro...
The poly(A)-binding protein (PABP), bound to the 3' poly(A) tail of eukaryotic mRNAs, plays critical roles in mRNA translation and stability. PABP autoregu... EO Melo,D Rafael,MDS Cezar,... 被引量: 0发表: 2021年 Relative role of genetic complement abnormalities in sporadic and famil...
Co-injection of poly(A)-binding protein (PABP) mRNA increased the function of the cap and poly(A) tail in promoting translation from poly(A)(+) but not poly(A)(-) mRNAs, particularly for mRNAs containing secondary structure. In the absence of an internal ribosome entry site, expression ...
greater reduction in translational efficiency when AtPAB is depleted.Our study provides a new mechanism that translational efficiency of a gene can be regulated through the G-content-dependent PAB binding, paving the way for a better understanding of poly(A) tail-associated regulation of gene ...
Moreover, the abundance of mRNA binding proteins, as well as translational activity and rate of poly(A) tail removal, are modulated and appear to influence transcript stability during liver regeneration. However, alteration of transcript stability is not the sole posttranscriptional mechanism regulating...
Poly(A) Tail Shortening by a Mammalian Poly(A)-specific 3′-Exoribonuclease 3'-Exonucleolytic removal of the poly(A) tail is the first and often rate-limiting step in the decay of many eucaryotic mRNAs. In a cytoplasmic extract fro... CG Körner,E Wahle - 《Journal of Biological Chemi...
Post-transcriptional polyadenylation of nascent transcripts through the addition of a polyadenylated tail to the 30-untranslated regions (UTR) is a key mRNA processing event in eukaryotic cells1. This reaction requires numerous trans-acting factors that are directed to poly(A) sites by cis-acting ...
A somewhat unexpected possible function of ACOT8 (Pte1) in Saccharomyces cerevisiae is the apparent involvement in the efficient metabolism of straight and methyl-branched short- to medium-chain fatty acids [44]. This study showed that polyhydroxyalkanoate synthesis and cell growth was somewhat impa...
Firstly, we made a mold of stretchable chamber and poured polydimethylsiloxane (PDMS) liquid (10:1 mixture of Dow Corning 184 gel and curing agent) into the mold. Then, we evacuated the air bubbles and baked the PDMS in the mold at 80 °C for 2 h. Afterward, the PDMS stretching...
(c) Shortening of HLA-A2 mRNA’s poly(A) tail is promoted by MEX-3C’s ubiquitin ligase activity. RT–PCR-based Poly(A) tail length assay (PAT) for HLA-A2 mRNA in control (EV/GFP), wild-type or RINGless MEX-3C-expressing (FACS sorted) cells (right panel). ACTIN mRNA was ...