The example of Parkinson's disease. Int J Pharm 381(2):113–121. : 10.1016/j.ijpharm.2009.03.003Preynat-Seauve O, et al. Pluripotent stem cells as new drugs? The example of Parkinson’s disease. Int J Pharm. 2009;381(2):113–21....
Human EC cells were subsequently derived, and these cells show surface marker expression that is different from mouse EC cells. For example, mouse EC cells express SSEA-1, while human EC cells express SSEA3, SSEA-4, TRA-1-60, and TRA-1-81. It remains unclear whether these differences ...
The human embryo undergoes morphogenetic transformations following implantation into the uterus, but our knowledge of this crucial stage is limited by the inability to observe the embryo in vivo. Models of the embryo derived from stem cells are important tools for interrogating developmental events and ...
Human pluripotent stem cells (PSCs) can give rise to any cell type in the body. PSC derivatives are being developed for therapeutic use in diseases affecting organs and organ systems such as the eye, nervous system, heart, pancreas, liver, intestines, lung, circulatory system and skin, as ...
Herein, we use cardiogenesis as an example to reveal the potential of these cells to better understand the first steps of cardiac development. 展开 关键词: valves cardiac development Stem cells DOI: 10.1051/jbio/2012001 被引量: 1 年份: 2012 ...
A stem-cell-based therapy could be the ultimate strategy for the regeneration of degenerated nervous tissues. While neural progenitor cells are limited, the generation of functional nervous tissue cells from non-neural somatic cells (for example, dental stem cells) is highly desired. The recent pub...
(3D) cell technology and future stem cell applications. Specifically, we highlight the following crucial domains: 1) sources of pluripotent cells; 2) next-generationin vivodirect reprogramming technology;3) cell types derived from PSCs and the influence of genetic memory; 4) induction of ...
we propose a better in-vitro understanding of the disease using a 3D lung organoid model derived from ethnicity-based induced pluripotent stem cells and the lung progenitor cells, namely the bronchial transient epithelial cells that are attacked more by the SARS-CoV2. So, it is important to und...
stem cellfunction is highly dysregulated during tumorigenesis.The cancer stem cell (CSC) hypothesis has become anattractive model to account for therapeutic failure in era-dicating highly malignant tumors. For example, it hasbeen hypothesized that rare CSC populations evade cur-rent treatment strategies...
The products of this method are termed induced pluripotent stem (iPS)" cells. iPS cells have considerable promise as a substitute for ES cells not only for regenerative medicine but also in many other fields. For example, liver and heart cells derived from iPS cells can be used in ...