英文摘要: OBJECTIVE: To prepare adriamycin-loaded PLGA-PLL-PEG nanoparticles, and study its antitumor activity. METHODS: PLGA-PLL-PEG with the polymerization of PLGA-PLL and activated polyethylene glycol was used as carrier for adriamycin, and adriamycin-loaded PLGA-PLL-PEG nanoparticles were prepared...
PLGA-based nanoparticles: An overview of biomedical applications[J]. Journal of Controlled Release, 2012, 161(2):505-522. [2] Makadia HK, Siegel SJ. Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier[J]. Polymers, 2011, 3(3):1377-1397. [3] Tian H,...
PLGA-PEG/PEI NANOPARTICLES AND METHODS OF USEProvided herein is a composition comprising a nanoparticle comprising poly(lactic acid-co-glycolic acid) (PLGA)-b-polyethylene glycol (PEG) (PLGA-PEG) copolymer formulated with polyethylenimine (PEI), and one or more cargo molecules (e.g., a nucleic...
参考文献: [1] Danhier F, Ansorena E, Silva JM, et al. PLGA-based nanoparticles: An overview of biomedical applications[J]. Journal of Controlled Release, 2012, 161(2):505-522. [2] Makadia HK, Siegel SJ. Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Car...
叶酸修饰的PEG化PLGA纳米粒(Folate-modified PEGylated PLGA nanoparticles, F-PEG-PLGA-NPs)是一种结合了叶酸(Folate)靶向性、聚乙二醇(PEG)稳定性和聚乳酸-羟基乙酸共聚物(PLGA)生物降解性和药物封装能力的纳米药物传递系统。以下是对这种纳米粒的详细解释: ...
Nanomedicine has been used in various cancer treatments, including tumor targeted drug delivery, thermotherapy and photodynamic therapy. PLGA material is a commonly used nano drug carrier. PLGA nanoparticles have the characteristics of good stability and long vascular circulation time, and are particularly...
Cell-mediated delivery of 润, 肺泡结构破坏, 微血栓形成; RNPs/CLT 组预处理 nanoparticles: taking advantage of circulatory cells to target 后大鼠肺组织间质水肿、出血及炎症细胞浸润等病理 nanoparticles [J]. J Control Release, 2014, 190: 531 541. 变化较模型组和 CLT 组明显减轻, 肺泡结构基本完 [...
2) PLGA/nanoparticles PLGA/纳米粒 3) PLGA nanospheres PLGA纳米粒 1. Epirubicin(EPI) loaded PLGA nanospheres were prepared by a solvent evaporation technique(W_1/O/W_2). 本研究选用W_1/O/W_2复乳法制备了载EPI的PLGA纳米粒,采用两种方法用GS修饰PLGA纳米粒表面:吸附的方法和共价交联的方法。
Injectable hydrogel loaded with doxorubicin and siRNA PLGA nanoparticle水凝胶 Injectable Hydrogel loaded with fluorinated hyaluronic acid nanoparticles水凝胶 Injectable Hydrogel loaded with trastuzumab microspheres水凝胶 Injectable hydrogel水凝胶上一篇:8ARM-PEG-DBCO 八臂-聚乙二醇-二苯基环辛炔 下一篇:水溶性In...
[1] Danhier F, Ansorena E, Silva JM, et al. PLGA-based nanoparticles: An overview of biomedical applications[J]. Journal of Controlled Release, 2012, 161(2):505-522. [2] Makadia HK, Siegel SJ. Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier[J]....