of the four phenolic groups increase, reaching four full negative charges at pH 10 (two pH units above the larger phenolic pKa 8). All the phenolic negative charges are located on the rigid peptidic basket. The phenol ring #5 is likely the more acidic one with a pKa of 7.0. However,...
enaminone (phenol ? quinone) equilibrium of the 1-hydroxy-2-naphthaldehyde Schiff base (2-phenyliminomethyl-naphthalen-1-ol) wa... PI Nagy,WMF Fabian - 《Journal of Physical Chemistry B》 被引量: 16发表: 2006年 In-Solution Conformational Analysis of the XCYCH3 Moiety for Small Esters and...
The one with a lower pKa value is more acidic. For example, which of the following two molecules is more acidic? The pKa of carboxylic acids is ~5 and the pKa of phenol is ~10. Therefore, propionic acid is 105 more acidic than phenol. What if there are more functional groups in the...
Cells need to coordinate gene expression with their metabolic states to maintain cell homeostasis and growth. How cells transduce nutrient availability to appropriate gene expression remains poorly understood. Here we show that glycolysis regulates histo
Given increasing risk of cadmium-induced neurotoxicity, the study was conducted to delineate the molecular mechanisms associated with cadmium-induced motor dysfunctions and identify targets that govern dopaminergic signaling in the brain involving in viv
(phenol) AP15 APPENDIX G Acid Dissociation Constants (Continued) harxxxxx_App-G.qxd 2/15/10 5:25 PM Page AP15 Ionic strength ( ) 0 0.1 M Name Structure pK a K a pK a HO 2 CCH 2 CO 2 H HSCH 2 CO 2 H 2-Mercaptoethanol HSCH 2 CH 2 OH 9.72 1.9 10 10 9.40 —— Methylami...
After digestion, the reaction mixtures were extracted with phenol and chloroform and precipitated with ethanol. The yield of the RNA product was determined by measuring optical density at 260 nm. The RNA was derivatized as described previously (Kang and Wang, 1994) with some modification. RNA (4...
Ssanghwa-tang (SHT) is a widely used medication for the treatment of fatigue, pain, inflammation, hypothermia, erectile dysfunction, cancer, and osteoporosis in Asia, however, role of SHT on the melanin synthesis has not been checked previously. Thus, the present study was designed to determine...