45 Single-molecule insights for DNA_RNA_protein interactions and drug discovery and 1:01:06 Skeleta for Monomial Quiver Relations 1:06:54 Solving clustering problems via new swarm intelligent algorithms 42:45 Statistical Network Models for Integrating Functional Connectivity with sMRI and 59:08 The ...
Fluorescent tags that can be attached to cellular proteins are an indispensable biological imaging tool, but are often large and can interfere with a protein's function. Smaller ones, meanwhile, can be toxic, as well as unreliable at labelling the protein of interest. Alice Ting and her team ...
Cover Picture: Direct Observation of Single Protein Molecules in Aqueous Solution (ChemPhysChem 4/2006)fluorescent probes •fluorescence spectroscopy •imaging agents •quantum dots •single-molecule studiesThe cover picture shows a surface plot representation of the trajectories of a single quantum ...
The d(CAG)n expansion mutation in the Huntington gene results in the production of aberrant protein that leads to gradual damage to specific areas of the brain. Although the actual mechanism of repeat expansion remains uncertain, repeat instability of CAG/CTG might be related to the increased ...
Sensitivityof Water Dynamics to Biologically SignificantSurfaces of Monomeric Insulin: Role of Topology and ElectrostaticInteractions. In addition to thebiologically active monomer of the protein insulincirculating in human blood, the molecule also exists in dimeric andhexameric forms that... Bagchi,Kushal...
An example of catabolic enzyme reaction in humans is the digestion process. The reaction in which an enzyme acts upon complex molecule called...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our...
When viruses attack, one molecule more than any other fights back. Interferon triggers the activation of more than 350 genes, and despite the obvious connection, the vast majority have never been tested for antiviral properties. A team of researchers, led by scientists from Rockefeller University,...
Different from the non-bonded interactions, these bonded terms describe the stiffer or harder degrees of freedom inside each molecule. Among the stiff degrees of freedom, the dihedral term is relatively soft, and plays a key role in the conformational flexibility of biological macromolecules and ...
This suggest that this agent may play a role in the management of patients with skin and lung disease who fail to respond to conventional immunosuppressive therapies [188]. There are high hopes for research on biological DMARDs (disease-modifying anti-rheumatic drugs) and small-molecule synthetic...
(Figure 4-1). The resulting molecule is found inribonucleic acidorRNA. If one hydroxyl (OH) group has been removed from the ribose, thedeoxyversions of the nucleoside and nucleotide form the building blocks ofdeoxyribonucleic acidorDNA(Figure 4-1). Each component of nucleosides and nucleotides ...