Prostate cancer cells survive and multiply because of androgens resulting from the conversion of testosterone by 5a-reductase enzymes. Thus, androgen deprivation therapy is used to treat the disease, however, resistant cancer cells continue to grow. Possible explanations for this have been studied, ...
The possible significance of intracellular events in prostate cancer development is considered with particular emphasis on those parameters which may reside outside the endocrine effects on the prostatic cells. 展开 关键词: steroid hormones metabolism hypothalamo‐hypophyseal‐gondadal‐axis ...
Studies are needed to investigate all aspects of hot flashes in populations other than those with breast cancer, such as men with prostate cancer, carcinoid tumors, medullary thyroid tumors, pancreatic islet-cell tumors, renal cell carcinoma, and phenochromocytoma. 展开 关键词:...
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This page is a summary of:Molecular biology and cellular physiology of refractoriness to androgen ablation therapy in advanced prostate cancer, Expert Opinion on Investigational Drugs, June 2001, Informa Healthcare, DOI:10.1517/13543784.10.6.1099. ...
Another common disorder involving the prostate is prostate cancer. According to the Centers for Disease Control and Prevention (CDC), prostate cancer is the second most common cancer in men. However, some forms of prostate cancer grow very slowly and thus may not ever require treatmen...
Radical prostatectomy is commonly used in the management of localized prostate cancer. Urinary incontinence after prostatectomy is of great concern to many patients. Improved understanding of the anatomy of the external urethral sphincter complex has resulted in a statistically significant decrease in the ...
A key determinant of this protection is the urokinase/plasmin cascade which modulates the local concentration of survival factors, such as insulin-like growth factor (IGF-1). The molecular pathways whereby this major growth and survival factor for prostate cancer cells exerts its anti-apoptotic ...
Prostate cancer, the most frequently diagnosed cancer in Western men, can display a high variability in term of clinical aggressiveness and prognosis and none of the available markers is able to accu...
Define Cell physiology. Cell physiology synonyms, Cell physiology pronunciation, Cell physiology translation, English dictionary definition of Cell physiology. n. 1. The biological study of the functions of living organisms and their parts. 2. All the fu