Gao. 1995. Altered physiology and ac- tion of insulin-like growth factor-1 in skeletal muscle in chronic renal failure. Am. J. Kidney Dis. 26:248-255.Kopple JD, Ding H, Gao XL. Altered physiology and action of insulin-like growth factor 1 in skeletal muscle in chronic renal failure. ...
insulin secretionislets of Langerhansnormal physiologySummary In normal subjects, circulating glucose concentrations are maintained within fairly narrow limits by endocrine systems that regulate glucose uptake into peripheral and hepatic tissues and control the release of glucose back into the circulation. Co...
Studies on the physiology of the liver. 24. The effect of insulin on the blood sugar following total removal of the pancreas and liver. Using a depancreatized dog, confirmation is obtained of the observation by Mann and Magath that insulin exerts its hypoglycaemic action in the absence of t...
The development of the chick embryo go- nads is influenced by gonadotropins (follicle-stimulating hormone (FSH), luteinizing hormone, human chorionic gonadotropin (hCG)). We have previously shown that insulin enhanced the production of androgens in the testis of the newly hatched chicken and increas...
Under physiological conditions, the release of insulin is ruled in an immediate and direct manner by nutrients, hormones and neurotransmitters and, in a delayed fashion, by a series of ontogenic, alimentary and endocrine factors (1). The recognition of D-glucose by the islet B-cells as a sti...
W. Time dependence of insulin action in muscle and adipose tissue in the rat in vivo. An increasing response in adipose tissue with time. Diabetes 34, 1049–1054 (1985). 21. Yore, M. M. et al. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory...
The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase. J Biol Chem. 2004;279(3):1713–9. Article CAS PubMed Google Scholar Wang W, Morrison B, Galbaugh T, Jose CC, Kenney N, Cutler ML....
Ahmad T et al (2004) The mitogenic action of insulin-like growth factor I in normal human mammary epithelial cells requires the epidermal growth factor receptor tyrosine kinase. J Biol Chem. 279(3):1713–9 CASPubMedGoogle Scholar Wang W et al (2008) Glucocorticoid induced expression of connec...
Studies with cultured cells and more recently with subcellular membrane preparations have revealed significant information about the mechanism of action of EGF. In particular, events which occur immediately upon the formation of hormone-receptor complexes have been described. The biochemical signaling that ...
Hepatoma cell lines are widely used to model the hepatocyte for insulin signaling and fatty liver disease. However, a direct comparison of insulin action in primary hepatocytes and in hepatoma cell lines is needed to validate this model and to better understand liver cancer. Here we have ...