Cancer cachexia is a debilitating consequence of disease progression, characterised by the significant weight loss through the catabolism of both skeletal muscle and adipose tissue, leading to a reduced mobility and muscle function, fatigue, impaired quality of life and ultimately death occurring with 25...
In contrast to existing options, clascoterone, a first-in-class antiandrogen, has proven to be both safe and effective for patients above the age of twelve, in both males and females. Our review examines clascoterone, delving into its preclinical pharmacology, pharmacokinetic properties, ...