The vibrational dynamics of a DNA molecule with counterions neutralizing the charged phosphate groups have been studied. With the help of elaborated model the conformational vibrations of the DNA double helix with alkaline metal ions have been described both qualitatively and quantitatively. For the ...
A phosphate group refers to a chemical group consisting of phosphorus and oxygen atoms. It is found in both DNA and RNA, where it is attached to the hydroxyl group of the sugar molecule. AI generated definition based on: Handbook of Biomolecules, 2023 ...
Accumulation of nucleotide building blocks prior to and during S phase facilitates DNA duplication. Herein, we find that the anaphase-promoting complex/cyclosome (APC/C) synchronizes ribose-5-phosphate levels and DNA synthesis during the cell cycle. In late G1and S phases, transketolase-like 1 (...
Furthermore, the assay can be modified to detect virtually any naturally occurring organic phosphate molecule by including an enzyme that can specifically digest the organic phosphate to liberate inorganic phosphate. In the PiPer phosphate assay ...
These bonds are called phosphodiester bonds, and the sugar-phosphate backbone is described as extending, or growing, in the 5' to 3' direction when the molecule is synthesized. In double-stranded DNA, the molecular double-helix shape is formed by two linear sugar-phosphate backbones that run...
The same molecule in melanoma models suppresses T cell proliferation and their ability to kill cancer cells [84]. Nucleotides and their degradation products are also believed to modulate communication between mPCs and normal cells, contributing to the immunocompromised state of MM patients [17,12...
Being the main molecule of life, DNA has a simple chemical structure that is surprisingly fit to the important biological functions that it performs. In spite of its simplicity, the molecular organization of DNA as a linear copolymer of ... V Poltev,VM Anisimov,V Dominguez,... 被引量: 0...
“DNA replication” and other terms that were related to the functioning of the cell machinery. The expression of 1256 genes were reduced to their basal levels. The most enriched term in this set of genes was “response to stimulus”. A similar analysis in the shoot revealed that there were...
A. Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis. Future. Oncol. 5, 1477–1486 (2009). Article CAS PubMed Google Scholar Melendez, A. J. & Khaw, A. K. Dichotomy of Ca2+ signals triggered by different phospholipid pathways...