The phosphate group of DNA as a potential target for RSU-1069, a nitroimidazole-aziridine radiosensitizer - Silver, O'Neill, et al. - 1986 () Citation Context ...y, but it is possible that the sensitivity of the unwinding assay for strand break detection is decreased because of the ...
Basic structure of DNA or deoxyribonucleic acid: A nucleotide is the basic of polynucleotide chain of DNA and each nucleotide is composed of three components - i) a nitrogenous base, ii) a pentose sugar and iii) a phosphate group. Nitrogen base is attached to the pentose sugar by an N-gl...
A phosphate group refers to a chemical group consisting of phosphorus and oxygen atoms. It is found in both DNA and RNA, where it is attached to the hydroxyl group of the sugar molecule. AI generated definition based on: Handbook of Biomolecules, 2023 ...
aBonbonnière 糖果箱子[translate] aThe phosphate group is then transferred to the regular protein(an activator or repressor), which changes shape to its DNA binding form. 磷酸盐小组然后转移到规则蛋白质(活化计或镇压者),改变形状对它的脱氧核糖核酸约束形式。[translate]...
DNA and RNA are composed of nucleotides that are linked to one another in a chain by chemical bonds, called ester bonds, between the sugar base of one nucleotide and the phosphate group of the adjacent nucleotide. The sugar is the 3' end, and the phosphate is the 5' end of each nuclei...
A nucleotide of DNA is made up of: a. A five-carbon sugar, a phosphate group, and one of four nitrogenous bases. b. A six-carbon sugar, a phosphate group, and one of twenty amino acids. c. A five-carbon sugar, a nitrogenous base,...
Assessment of heat-sensitive thiophosphate protecting groups in the development of thermolytic DNA oligonucleotide prodrugs Heat-sensitive thiophosphate protecting groups derived from the alcohol 4 or 10 have provided insights in the design of DNA oligonucleotide prodrugs. Indee......
Several other DNA-protein complexes are listed as examples of possible asymmetric charge-induced bending.doi:10.1080/07391102.1989.10506519Manning, Gerald S.Ebralidse, K. K.Mirzabekov, A. D.Rich, AlexanderTaylor & Francis GroupJournal of Biomolecular Structure & Dynamics...
Introduction to the Structure, Properties, and Reactions of DNA Richard R.Sinden, inDNA Structure and Function, 1994 a.Ribose Sugar Is Found in RNA The source of theribose(or deoxyribose) sugar in the biochemical synthesis of purines andpyrimidinesis 5-phosphoribosylpyrophosphate(PRPP), which is...
In aqueous environments, EDC (Chapter 4, Section 1.1) may be used to couple amine-containing compounds to the terminal phosphate group of an oligonucleotide, forming a phosphoramidate linkage. In DNA or RNA chains, the internal phosphate groups do not react under the pH conditions of the ...