ArticleCASPubMedGoogle Scholar Anderson BJ, Gunn TR, Holford NH, Johnson R. Caffeine overdose in a premature infant: clinical course and pharmacokinetics. Anaesth Intens Care. 1999;27(3):307–11. CASGoogle Scholar Anderson BJ, Holford NH, Woollard GA. Aspects of theophylline clearance in childre...
Introduction: Parkinson's disease is a chronic, neurodegenerative disease entity with heterogeneous features and course. Levodopa is the most efficacious dopamine substituting drug. Particularly, long term application of oral levodopa/decarboxylase inhibitor formulations sooner or later supports onset of ...
Anakinra in the treatment of polyarticular-course juvenile rheumatoid arthritis: safety and preliminary efficacy results of a randomized multicenter study. Clin Rheumatol. 2009;28(2):129–37. https://doi.org/10.1007/s10067-008-0995-9. Article PubMed Google Scholar Anderson HL, Coran AG, Drong...
For patients with hypotension or hyperlactatemia, immunomodulatory therapy is advocated, which is often given as a short course of hydrocortisone. Although many therapeutic agents for the treatment of sepsis have been evaluated, no specific antiseptic agent has been approved[4]. In China, XueBiJing...
(ART) for pregnant and breastfeeding women living with HIV and short-course infant prophylaxis in HIV-1 exposed born negative newborns, and exclusive breastfeeding during the first 6 months to reduce vertical transmis- sion of HIV-1 (MTCT) and optimize child survival (https://www....
In the multiple-dose study, no serious clinical or labora- tory events were observed during the course of the study. In summary, following multiple injections of a dose of 1.0 mg/kg weekly for 4 weeks, the patients were generally safe. How- Acta Pharmacologica Sinica www.chinaphar.com Li ...
Inclusion Online Commenting Policy Public Access and Open Access Policy Statement on Potentially Offensive Content JAMA Network Products AMA Manual of Style JAMAevidence Peer Review Congress JN Learning Home State CME Clinical Challenge CME Atrial Fibrillation Course Women's Health Course CME / MOC Report...
Therefore, physiologically based pharmacokinetic (PBPK) models that are capable of providing a priori prediction of the time course of chemicals in blood and tissues is of tremendous interest [4]. PBPK models are mechanistically based mathematical descriptions of the absorption, distribution, metabolism,...
To date, pharmacokinetics has been proven to be an efficacious approach to exploring the intracorporal course of drugs, especially absorption characteristics12. Metabolomics, a systems biology approach, is characterized by a holistic perspective consistent with the integral principle of TCM. The system-...
(12 mg/mL), and of course propofol as the active ingredient [12]. After a series of reports of bacterial contamination of opened ampoules, ethylenediaminetetraacetic acid (EDTA; 0.05 mg/mL) was added to the formulation in 1996 [13], and is still sold in some but not all countries. The...