Phage Treatment of Human Infections. Bacteriophage 1(2) 2011: 66-85.Abedon, S.T. et al. 2011. Phage treatment of human infec- tions. Bacteriophage 1: 66-85.Phage treatment of human infections[J] . Stephen T. Abedon,Sarah J. Kuhl,Bob G. Blasdel,Elizabeth Martin Kutter.Bacteriophage ....
Phage treatment of human infections - Bacteriophage - Volume 1, Issue 2 Phages as bactericidal agents have been employed for 90 years as a means of treating bacterial infections in humans as well as other species, a process kno... ST Abedon,SJ Kuhl,BG Blasdel,... - 《Bacteriophage》 被...
Phage treatment of human infections. Bacteriophage. 2011;1:66–85. Article PubMed PubMed Central Google Scholar Gordillo Altamirano FL, Barr JJ. Phage therapy in the postantibiotic era. Clin Microbiol Rev. 2019;32:e00066-18. Cisek AA, Dąbrowska I, Gregorczyk KP, Wyżewski Z. Phage ...
Phage therapy uses bacteriophages to target bacteria and treat infections. In this Primer, Skurnik et al. discuss the practical aspects of phage therapy, from the microbiological methods used to prepare and characterize phages to the selection of therapeutic phages for clinical applications. Mikael Skur...
The treatment of diabetic foot infections (DFIs) represents a costly and growing challenge to the NHS. DFIs can be difficult to treat for a variety of reasons, including late presentation of advanced infection, and antibiotic tolerance or resistance. Bacteriophage (phage) are ubiquitous viruses tha...
Phage Therapy in Clinical Practice: Treatment of Human Infections Phage therapy is the application of bacteria-specific viruses with the goal of reducing or eliminating pathogenic or nuisance bacteria. While phage therapy... E Kutter,D De Vos,G Gvasalia,... - 《Current Pharmaceutical Biotechnology...
The use of phage-encoded lytic protein-endolysin instead of phages for MDR bacterial treatment [28]. Endolysins are a group of viral hydrolytic enzymes responsible for degrading the bacterial cell wall peptidoglycan layer (PG) during the replication cycle, thereby releasing viral progeny. They ...
specificity.Phages can penetrate biofilms, offering a solution where antibiotics often fail.Personalized phage therapy tailors treatment to individual bacterial infections.Regulatory challenges hinder phage therapy's widespread clinical adoption.Phage therapy poses lower risks of disrupting the host's beneficial...
Phage therapy has been a valuable asset since the 1920s to deal with pathogenic bacterial infections, and has been practised ever since, especially in the former Soviet Union and in eastern Europe. The western world remained sceptical and resorted to the widespread use of antibiotics as soon as...
Phage predation is generally assumed to reduce microbial proliferation while not contributing to the spread of antibiotic resistance. However, this assumption does not consider the effect of phage predation on the spatial organization of different microb