However, while personalized phage therapy is associated with improved outcomes in individual cases, clinical trials demonstrating treatment efficacy are lacking, limiting the therapeutic potential of this approach for respiratory infections. In this review, we address the current state of phage therapy for...
Bacteriohage (phage) therapy is regaining attention as a potential treatment option for bacterial infections, including those caused by multidrug-resistant (MDR) bacteria. Phage therapy utilizes obligatory lytic phages to kill its host, bacteria. During the lytic cycle of infection, a phage self-repl...
Chang RYK, Wallin M, Lin Y, Leung SSY, Wang H, Morales S, Chan HK (2018) Phage therapy for respiratory infections. Adv Drug Deliv Rev 133:76–86 CAS PubMed PubMed Central Google Scholar Chattopadhyay D, Puls RW (2000) Forces dictating colloidal interactions between viruses and soil. Ch...
The adoption of therapy based on bacteriophage for the reduction of harboured pathogens is limited by a lack of understanding regarding their formulation as medicines. The product must able to efficiently deliver phage without deterioration and since oral delivery results in the destruction of the lyti...
The phage therapy market is experiencing significant growth due to the increasing prevalence of antibiotic-resistant infections and the growing interest in...
Nevertheless, animal models provide vitally useful data on efficacy and safety of phage therapy in living hosts and are crucial for further development of the approach. Systemic Infections Several studies have investigated the efficacy of phage therapy for treatment of systemic infections. In a gut-...
摘要: The potential of aerosol phage therapy for treating lung infections has been demonstrated in animal models and clinical studies. This work compared the performance of two dry powde... 查看全部>>关键词: aerosols antibiotic-resistant bacteria phage therapy pulmonary infections ...
Objectives Phage therapy has shown a great promise for the treatment of multidrug-resistant bacterial infections. However, the lack of a thorough and organ... X Tan,K Chen,Z Jiang,... - 《Biorxiv》 被引量: 0发表: 2023年 Bacteriophages for bronchiectasis: treatment of the future? phage the...
Phage therapy for respiratory infections Adv. Drug Deliv. Rev., 133 (2018), pp. 76-86 View PDFView articleView in ScopusGoogle Scholar 38 M. Trepel, W. Arap, R. Pasqualini Modulation of the immune response by systemic targeting of antigens to lymph nodes Cancer Res., 61 (2001), pp....
A significant focus of phage therapy studies in animals has been around respiratory infections, gastrointestinal infections and infections of the skin and wounds (Table 1). Phage therapy studies with animals has shown that in certain instances, it may help in reducing the densities of the infecting...