The phage therapy market is experiencing significant growth due to the increasing prevalence of antibiotic-resistant infections and the growing interest in alternative treatments. Advances in biotechnology and ongoing research are driving innovation in...
Although bacteriophages are not pathogenic to mammalian cells, they induce a humoral immune response in a mammalian host resulting in the formation of anti-phage antibodies that can influence the effect of phage therapy. We detail the experiences of several centers in Poland, the Republic of ...
In phage therapy, phages are used to reduce bacterial numbers, thereby curing bacterial infections. Although this principle is conceptually straightforward, its practical application faces several hurdles. In this Primer, the practical aspects of phage therapy are outlined. We introduce the microbiological...
University of California, San Diego, USA Introduction to Targeting Phage Therapy 2024 Marvin Edeas INSERM – Institut Cochin, Université de Paris, France Adaptive Phage Therapy in The Intensive Care Unit: From Science to Patients Ekaterina Chernevskaya Federal Research and Clinical Center of Intens...
Viruses that infect bacteria (bacteriophages; also known as phages) were discovered 100 years ago. Since then, phage research has transformed fundamental and translational biosciences. For example, phages were crucial in establishing the central dogma of molecular biology — information is sequentially pa...
Laboratory for Genetics of Microorganisms and Bacteriophages, Eliava Institute of Bacteriophage, Microbiology & Virology, Tbilisi, GA, USA. n_chanish.ibmv@caucasus.netAdvances in virus researchChanishvili N. 2012. Phage therapy-history from Twort and d'Herelle through Soviet experience to current...
Phage therapy: a renewed approach to combat antibiotic-resistant bacteria Cell Host Microbe (2019) R.N. Strange et al. Plant disease: a threat to global food security Annu. Rev. Phytopathol. (2005) J. Kohl Mode of action of microbial biological control agents against plant diseases: relevance...
Invitris MicrobiotiX Sciensano TechnoPhage Vivantes Laboratorios Syva ACD Pharma Atlantic Technological University Agricultural University of Athens Agricultural University of Georgia Bermuda Government BG Klinikum Bergmannstrost Halle Centro De Calidad Avícola Y Alimentación Animal De La Comunidad Valenciana ...
There are also studies that have shown that phage therapy is ineffective. Several studies of oral use of E. coli T4-like phages in adult and child patients with bacterial diarrhea have shown no serious adverse effects, but no efficacy has been observed [85,86]. PreforPro, a phage mixture...
Pharmaceutical legislation and regulation were designed to serve pharmaceutical industries and large-scale production, not customized products, and there is no compatible regulatory framework for phage therapy in many countries. However, many successful models have been developed to employ phages in ...