phage - a virus that is parasitic (reproduces itself) in bacteria; "phage uses the bacterium's machinery and energy to produce more phage until the bacterium is destroyed and phage is released to invade surrounding bacteria" bacteriophage virus - (virology) ultramicroscopic infectious agent that ...
Editorial: Phage therapy: past, present and future. Front Microbiol 8, 981 (2017). Article Google Scholar Denyes, J. M. et al. Modified Bacteriophage S16 Long Tail Fiber Proteins for Rapid and Specific Immobilization and Detection of Salmonella Cells. Appl. Environ. Microbiol. 83, e00277-...
Canada; 2Environment and Sustainability Institute, Biosciences, University of Exeter, Penryn, UK; 3Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, ON, Canada; 4Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada; 5Department...
With the increase in antimicrobial resistance and subsequent need for alternatives to traditional antibiotics, phage therapy (PT) has gained a renewed interest. Much like antibiotics, bacteriophages or simply phages, have shown promise in eradicating bacterial infections; however, their fundamental ...
bacteriophage and cured children suffering from shigellosis.2However, the discovery of penicillin in 1928 and the generalization of anti-infectious treatments, a symbol of modernity, overshadowed phage therapy for a time, particularly in Western bloc countries such as the United States, Canada, and ...
In recent years, interest in phages has increased not only because of their potential use as alternatives to antibiotics (phage therapy) but also because of their applications in many other fields (phage display, immunology, microbial genetics, diagnostics, vaccine development, biosensors, etc.). ...
Although research on phage-based biopesticides temporarily stopped with the advent of antibiotics, the appearance of antibiotic resistant bacterial strains led to a renewed interest in phage therapy for control of plant diseases. In the past twenty years numerous successful experiments have been reported...
[7,8,9]. Growing evidence has suggested the application of phages in anti-infective therapy [10], recombinant antibody development [11], and food industry biocontrol [12]. Accumulating studies have focused on the pig gut microbiome because pig provides meat for human consumption and is also an...
View in ScopusGoogle Scholar Lehman, 2007 S. Lehman PhD thesis Brock University, Ontario, Canada (2007) Google Scholar Loc-Carrillo and Abedon, 2011 C. Loc-Carrillo, S.T. Abedon Pros and cons of phage therapy Bacteriophage, 1 (2011), pp. 111-114, 10.4161/bact.1.2.14590 Google Scholar...
Despite all of the documented cases of patients being successfully treated with phages, the introduction of phage therapy in Western countries still faces major obstacles, due especially to regulatory issues [37], such as the very strict guidelines of the US FDA (Food and Drug Administration), ...