Here, we present HostPhinder, a tool aimed at predicting the bacterial host of phages by examining the phage genome sequence. Using a reference database of 2196 phages with known hosts, HostPhinder predicts the host species of a query phage as the host of the most genomically similar ...
Phage therapy has become one of the most promising alternatives to antibiotics in the treatment of bacterial diseases, and identifying phage-host interactions (PHIs) helps to understand the possible mechanism through which a phage infects bacteria to guide the development of phage therapy. Compared ...
About PHAGE PHAGE analyzes the waveform of vital data such as blood sugar levels using an index, accumulates the data, and implements products. It develops a diabetes treatment application equipped with an automatic prediction function for blood sugar levels. The company was founded in 2021 and is...
Surface, secreted and transmembrane protein-encoding open reading frames, collectively the secretome, can be identified in bacterial genome sequences using bioinformatics. However, functional analysis of translated secretomes is possible only if many sec
PhageHostLearn This is the repository related to our manuscript published in Nature Communications: "Prediction of Klebsiella phage-host specificity at the strain level", authored by Boeckaerts D, Stock M, Ferriol-González C, Jesús O-I, Sanjuan R, Domingo-Calap P, De Baets B and Briers ...
lifestyle prediction, host prediction, and functional annotation of gut phages in pigs. The data demonstrated that ARGs were also enriched in the gut phages and the most abundant antimicrobial resistance genotype was diaminopyrimidine resistance. These findings showed the communities and functions of gut...
Prediction of strain level phage–host interactions across theEscherichiagenus using only genomic informationdoi:10.1038/s41564-024-01832-5Predicting bacteriophage infection of specific bacterial strains promises advancements in phage therapy and microbial ecology. Whether the dynamics of well-established phage...
Klebsiella aerogenes is an opportunistic pathogen that causes a wide variety of infections. Due to the rising problem of antibiotic resistance, novel antibiotics and strategies to combat bacterial infections are needed. Host-specific bacteriophages are n
Only the vOTUs represented by a UViG with completeness ≥ 90% (i.e., representing a high-quality draft genome [28]) were used in downstream analyses to maximize the prediction accuracy of the software employed. The metadata requested by MIUViG standards for the vOTU-representative UViGs ...
query short spacer sequences. It introduces a novel approach of aggregating sets of spacer-based hits to discover phage-host matches. SpacePHARER is GPLv3-licensed open source software implemented in C++ and available for Linux and macOS. The software is designed to run efficiently on multiple ...