PHASTER (PHAge Search Tool - Enhanced Release) is a significant upgrade to the popular PHAST web server for the rapid identification and annotation of prophage sequences within bacterial genomes and plasmids. Although the steps in the phage identification pipeline in PHASTER remain largely the same ...
(PHAgeSearchTool–EnhancedRelease)isasignificantupgradetothepopularPHASTwebserverfortherapididentificationandannotationofprophagesequenceswithinbacterialgenomesandplasmids.Althoughthestepsinthephageidentifica-tionpipelineinPHASTERremainlargelythesameasintheoriginalPHAST,numeroussoftwareimprove-mentsandsignificant...
within which it would be impractical to analyze every possible reading frame. Taking 50 kb as an upper limit, we analyzed 16 of the no-spanin genomes with the LipoSearch tool [51], which inspects for potential
Phages’ physical form as a proteinaceous particle allows functional and programmed decoration of its surface that can confer the ability to penetrate biofilms, better control of in situ targeting, and enhanced pharmacokinetic (PK) and pharmacodynamic (PD) properties (Dąbrowska, 2019; Dąbrowska ...
[13]. Dynamics in natural ecosystems are mediated by phage-host interactions, and phage predation has the potential to be exploited for use in industrial and biomedical applications.R. opacusphage Toil has been used as a bioextraction agent for biodiesel production, forcing the release of ...
coli. Overall, by shuffling endolysin components we enhanced the antibacterial activity of Innolysins and showed that Innolysins can be used as antibacterials to kill at least a subset of antibiotic-resistant E. coli. Figure 7 Alignment of E. coli BL21 FhuA with homologous proteins of E. ...
leading to enhanced GTP hydrolysis activity. The PT-stimulated GTPase activity triggers a closed-to-open structural change in SspE, leading to the dissociation of SspE from self-DNA and activation of the C-terminal nuclease activity. Notably, the 5′-CPSCA-3′ modification induces only a modera...
Tech M, Merkl R: YACOP: Enhanced gene prediction obtained by a combination of existing methods. In Silico Biol 2003, 3: 441–51. CAS PubMed Google Scholar Chen LL, Ou HY, Zhang R, Zhang CT: ZCURVE_CoV: a new system to recognize protein coding genes in coronavirus genomes, and its...
with enhanced sensitivity and specificity comparing to current methods that primarily rely on multiple washing steps or limiting dilution. Using HUVEC cells as a selection, they isolated 21 phage clones bound to starved HUVECs and to VEGF-stimulated HUVECs. Fourteen clones (67%) had a >150% enh...
with enhanced sensitivity and specificity comparing to current methods that primarily rely on multiple washing steps or limiting dilution. Using HUVEC cells as a selection, they isolated 21 phage clones bound to starved HUVECs and to VEGF-stimulated HUVECs. Fourteen clones (67%) had a >150% enh...