New applications for phage integrases. J. Mol. Biol. 426, 2703-2716.Fogg PCM, Colloms SD, Rosser SJ, Stark WM, Smith MCM: New applications for phage integrases. J. Mol. Biol. 2014, 426:2703- 2716.P. Fogg, S. Colloms, S. Rosser, M. Stark and M. Smith, "New applica- tions ...
9,12. Moreover, we aimed to better understand the underlying functional and probiotic properties of these plasmids using curing plasmid experiments; in particular, we examined their physiological traits in metal tolerance and biosorption, antimicrobial ...
28,29, suggesting a dependence on host-specific machinery25,30. Since recombineering was first applied inE.coli31,32, a few other phage homologous recombination systems have been found to promote recombination in
We also investigated newly and previously sequencedF. prausnitziigenomes for the presence of prophages. A total of 89 prophage and prophage-like elements were identified in the genomes of 31 F. prausnitziistrains (1–6 elements per strain), with sizes ranging from 6.3 to 64.6 kb. These p...
However, before a phage can be proposed as a therapeutic candidate, it must be ensured that it carries no virulence or antibiotic resistance genes, integrases, or repressors of the lytic cycle (temperate phages need to be ruled out). Neither can they be transducer phages (to avoid gene ...