Lo J, Peng RH, Barker T, Xia CQ, Clare-Salzler MJ (2006) Peptide- pulsed immature dendritic cells reduce response to beta cell tar- get antigens and protect NOD recipients from type I diabetes. Ann N Y Acad Sci 1079:153-156Lo J, Peng RH, Barker T, Xia CQ, Clare-Salzler MJ (...
Phase I study in mel- anoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34ϩ hematopoietic progenitor cells. Int. J. Cancer 86: 385-392.Mackensen A, Herbst B, Chen JL, Kohler G, Noppen C, Herr W, Spagnoli GC, Cerundolo V, Lindema...
(2007) Vaccination with p53 peptide-pulsed dendritic cells is associated with disease stabilization in patients with p53 expressing advanced breast cancer; monitoring of serum YKL-40 and IL-6 as response biomarkers. Cancer Immunol Immunother 56: 1485-1499....
Generation of Immunostimulatory Dendritic Cells from Human CD34+ Hematopoietic Progenitor Cells of the Bone Marrow and Peripheral Blood Dendritic antigen-presenting cells are considered to be the most effective stimulators of T cell immunity. The use of dendritic cells has been proposed to ... H Ber...
Dendritic cells (DC) are potent antigen-presenting cells (APCs) capable of priming CTL responses in vivo. Here we show that major histocompatibility complex class I-presented peptide antigen pulsed onto dendritic APCs induces protective immunity to lethal challenge by a tumor transfected with the ...
Immunization with Epstein-Barr Virus (EBV) Peptide-pulsed Dendritic Cells Induces Functional CD8+ T-Cell Immunity and May Lead to Tumor Regression in Patie... et al.Immunization with Epstein-Barr Virus(EBV) peptide-pulsed dendritic cells induces functional CD8+ T-cell immunity and may lead to ...
sed dendritic cells Immunotherapy of malignant diseases with peptide pulsed dendritic cellsImmunotherapy of malignant diseases with peptide pulsed dendritic cellsdoi:10.1016/S0959-8049(01)80391-9PeterBrossartSDOSEuropean Journal of Cancer
cells was tested by ELISPOT.Results Of the five epitopes of heparanase,only Hpa(525-533),Hpa(277-285) and Hpa(405-413) could elicit potent specific lysis to KATO-Ⅲ,U2OS and SW480 cells which were heparanase and HLA-A2 positive.Effector induced by the above epitopes could not only lyse ...
Dendritic cells (DC) are the primary APC responsible for the capture of allergens in the airways and the shuttling of processed allergens to the draining lymph nodes where Ag presentation and T cell activation take place. The mechanism of this Ag handling and presentation in asthma is poorly und...
Dendritic cells, the most potent ‘professional’ antigen-presenting cells, hold promise for improving the immunotherapy of cancer. In three different well-characterized tumour models, naive mice injected with bone marrow-derived dendritic cells prepulse