peptide-pulsed 肽冲击，主要指（抗原）肽冲击靶细胞以获得免疫等应答的一种研究方式。肽-脉冲，这个词专业性太强了
Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor alpha2 chain in recurrent malignant glioma patients with HLA-A*24/A*02 allele. Cytotherapy. 2012;14(6):733 -742.Iwami K, Shimato S, Ohno M, Okada H, Nakahara N, Sato Y, et al. Peptide-pulsed dendritic cell ...
Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34ϩ hematopoietic progenitor cells. Int J Cancer 2000; 86:385-92.Mackensen, A., B. Herbst, J. L. Chen, G. Kohler, C. Noppen, W. Herr, G. C. Spagnoli, V....
Tuettenberg A,Jonuleit H,Tuting T,et al.Priming of T cells with Ad-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor-specific CD8+ T cells: implications for an efficient vaccination strategy. Gene Therapy . 2003...
Peptide-pulsed immature dendritic cells reduce response to beta cell target antigens and protect NOD recipients from type I diabetes. J. Clare-Salzler, "Peptide-pulsed immature dendritic cells reduce response to β cell target antigens and protect NOD recipients from type I diabetes," ... LO ...
Bossi G, Gerry AB, Paston SJ, Sutton DH, Hassan NJ, Jakobsen BK. Examining the presentation of tumor-associated antigens on peptide- pulsed T2 cells. Oncoimmunology 2013;2:e26840.Bossi G, Gerry AB, Paston SJ, Sutton DH, Hassan NJ, Jakobsen BK. Examining the presentation of tumor-...
Vaccination with p53 peptide-pulsed dendritic cells is associated with disease stabilization in patients with p53 expressing advanced breast cancer; monitoring of serum YKL-40 and IL-6 as response biomarkers. Cancer Immunol Immunother. 2007; 56 :1485–1499. [ PubMed ]...
The objectives of this study were to assess the toxicity and immunological response induced by the intra-dermal (i.d.) administration of MUC1-peptide-pulsed dendritic cells (DCs) in advanced pancreatic cancer patients. Patients with recurrent lesions or metastasis after surgery, and ...
On day 7, non-adherent cells were re-stimulated with peptide-pulsed adherent cells. On day14, responder cells (1 × 104/well) were incubated with peptide-pulsed target cells (1 × 105/well; .221A201 cells for HLA-A2 peptide or TISI cells for HLA-A24 peptide) in a 96-well culture ...
Immune and clinical outcomes in patients with stage IV melanoma vaccinated with peptide-pulsed dendritic cells derived from CD34+ progenitors and activated... Twenty-two HLA A*0201 patients with stage IV melanoma were enrolled in a phase 1 safety and feasibility trial using a composite dendritic ...