SpecificitySPDL1 shRNA Plasmid (Mouse) contains 3 different target-specific plasmids each encoding 19-23 nt (plus hairpin) shRNAs designed to knock down gene expression. Each plasmid contains a resistance gene for the selection of cells stably expressing shRNA. ...
GeneSymbolCd274(CD274antigen) Chromosome19 StrainofOriginC57BL/6J PD-L1(programmedcelldeathligand-1,又名CD274)是PD-1两个配体之一,主要表达于抗原 递呈细胞、激活T细胞及其他免疫细胞上。PD-L1在多种肿瘤中高表达,与PD-1相互作用后可以产生 抑制性信号,抑制T细胞增生,造成免疫逃逸。 构建策略 图1.PD-L1人源...