PD1-IL2v is currently being tested in a Ph1 clinical trial.doi:10.1158/1538-7445.AM2021-ND03Pablo UmanaAmerican Association for Cancer Research (AACR)Cancer research
It is undisputed that CD8 T cells play a critical role in controlling tumor growth and killing tumor cells, and that tumor specific T cells are essential for clinical responses to immune checkpoint inhibitors. Yet, the induction and maintenance of functional tumor antigen specific T cell responses...