[4]Bang YJ, Van Cutsem E, Feyereislova A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet. 2010 Aug 28;376(97...
P., Yang, Y., Nickles, D., and Cubas, R. (2019). Anti–PD-L1 treatment results in functional remodeling of the macrophage compartment. Cancer Res. 79, 1493–1506. https://doi.org/10.1158/0008-5472.CAN-18-3208.想
2. Neri, D., and Sondel, P.M. (2016). Immunocytokines for cancer treatment: past, present and future.Curr. Opin. Immunol.40, 96–102. https://doi.org/ 10.1016/j.coi.2016.03.006. 3. Spolski, R., Li, P., and Leonard, W.J. (2018). Biology and regulation of IL-2: from m...
P., Yang, Y., Nickles, D., and Cubas, R. (2019). Anti–PD-L1 treatment results in functional remodeling of the macrophage compartment.Cancer Res.79, 1493–1506. https://doi.org/10.1158/0008-5472.CAN-18-3208.
参考文献:Yang Song et al, Case Report: Genetic and immune microenvironmental characteristics of a rectal cancer patient with MSS/PD-L1-negative recurrent hepatopulmonary metastasis who achieved complete remission after treatment with PD-1 inhibitor, Front Immunol. 2023 Jul 13;
1.http://www.theguardian.com/science/2015/jun/01/immunotherapy-the-big-new-hope-for-cancer-treatment 2.http://www.cell.com/trends/cancer/abstract/S2405-8033(15)00019-9 3.http://www.sohu.com/a/313913808_100038690 4.https://www.nejm.o...
要知道Cervical Cancer历史数据anti-PD1的ORR只有百分之十几。(德琪JPM Presentation)遇事不决肠道菌群:19...
The disclosure relates to anti-pd1 antibody molecules and anti Lag3 antibody molecules. In particular, a composition comprising such an antibody molecule is also claimed for therapeutic purposes in the field of cancer disorders.ツェットル,マルクス...
[1]Pan QZ, Zhao JJ, Liu L, et al. XELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase...
Recently developed PD1 pathway inhibitors have revolutionized cancer treatment for some patients, but the majority of patients do not show complete responses, and adverse events have been noted. This Review discusses the diverse roles of the PD1 pathway in regulating immune responses and how this ...