And then, we used invasion assay to analyze that arecoline could stimulate PC3 cell invasion. In recent decade, the cancer metastasis and invasion evidences were correlated with epithelial mesenchymal transition (EMT). In which, cell morphology was transformed from epithelial to mesenchymal before ...
The nanoemulsion systems were characterized for surface morphology, droplet size, polydispersity index, zeta potential,in vitrorelease profile and the formulations were optimized. The anticancer potential of optimized nanoemulsion was evaluated by cells viability (MTT) assay, nuclear condensation, and ROS ...
In this study, we generated an iPSC line carrying a heterozygous mutation (c. 772+1G > A) in MyBPC3 gene. ZZUSAHi025-A, which is the generated iPSC line in the present study, showed a typical iPSC morphology such as polygonal shape, refractive edges, colony appearance and high nuclear/...
Since size and morphology of cells grown in vitro seem to be very dependent on seeding and growth conditions, it seems necessary to independently assay the size and shape to generate a representative model for the specific irradiation conditions of an experiment. The 241Am source used here has ...
Unlike wild-type or α1SDHPR-null MDG myoblasts, MDG/TRPC3 KD myoblasts exhibited dramatic changes in cellular morphology (e.g., un- usual expansion of both cell volume and the plasma membrane, and multi-nuclei) and failed to differentiate into myotubes possibly due to increased Ca2+ content...
Mycoplasma Status:Negative Storage:Liquid nitrogen II. Description of Host Cell Line Organism:Homo sapiens,human Tissue:Prostate Disease:Human Caucasian Prostate adenocarcinoma Morphology:Epithelial Growth Properties:Adherent III. Representative Data Figure.Detect Luciferase assay by Promega Bright-Glo Luciferase...
(ECM) proteins. However, whether PC3 cells increase or reduce adhesion and by which mechanisms they change adhesion to the ECM remains to be characterized. Here, we assay how ephrin-A1 stimulates PC3 cells to adhere to ECM proteins using single-cell force spectroscopy. We find that PC3 cells...
低浓度的双环铂可引起PC3细胞G2期阻滞,随药物浓度的升高sub-G1期细胞比例明显增加.结论 体外实验显示双环铂可诱导PC3细胞的凋亡,双环铂对细胞周期的影响可视为其抗肿瘤活性的机制之一.%Objective To investigate the apoptosis-inducing effect of dicycloplatin in androgen independent prostate cancer line PC3, and...
Histological sections of 8-week-old BLSW ears revealed a normal morphology of the organ of Corti and the spiral ganglion. At 52 weeks of age, there was a significant degeneration of the organ of Corti starting at the base and progressing towards the apex. Concomitantly, the spiral gan- g...
The inner cell preserves its morphology and maintains proper mitochondrial potential while being inside another cell. As a result of entosis the inner cell may undergo lysosomal degradation, mitotic division or leaving the outer cell with no harmful effects. Two last options prove that the condition...