E. 2013. Brain areas and pathways in the regulation of glucose metabolism. Biofactors, 39, 505-513.Charlene Diepenbroek , Mireille J. Serlie , Eric Fliers , Andries Kalsbeek , Susanne E. la Fleur . (2013) Brain areas and pathways in the regulation of glucose metabolism. BioFactors 39 ,...
Figure 2. NRF2 Knockdown Alters Glucose and Glutamine Metabolism in A549 Cells (A) Metabolic enzymes regulated by NRF2 in glucose metabolism. (B and C) Quantification of metabolic intermediates in glycolysis (B) and the PPP and purine nucleotide synthesis (C). Metabolite concentrations were quantifi...
4) metabolism, as well as including multiple amino acids (see Supplementary Material 1 and Fig. 1 for graphs of all significantly altered metabolites). Multiple metabolites involved in glycolysis were found to be increased in at least one brain region, including glucose, fructose, fructose-6-...
1). The process in which glucose was converted to glucose-6-phosphate (G6P), which is catalyzed by HK, is the first committed step in glucose metabolism with the production of ATP to meet the energy needs of cancer cells. HK2 is required for initiation and maintenance of BC [17]. Raya...
effectors, such as downstream enzymes and ion channels.31,32,33Therefore, the modular structure of the signaling system mediated by GPCR and G protein is vital for its role. In GPCRs, there are several receptors worth paying attention to, and the following are related to glucose metabolism: ...
The ring forms, which predominate in solution, may exist in two different stereoisomeric forms called alpha and beta (Figure 3). The treatment of tautomerism and anomerism is far from trivial and will be discussed in a separate publication. Figure 3 Different variants of D-glucose with their ...
metabolism during growth on excess glucose, redirecting carbon towards by-products of metabolism such as ethanol, acetate and glycerol, at the cost of biomass formation. Despite being an extensively studied system, knowledge on yeast glucose repression is still far from complete and key questions ...
Further, although some authors argued that atypical antipsychotics impact glucose sensitivity and induce insulin resistance even after a single dose [9], a major part of the studies point to a dose- and time-dependent effect of antipsychotics on glucose metabolism, with the greatest effect noted ...
AA metabolism in human health, cardiovascular and cancer biology, and the signaling pathways involved in these processes. To explore the role of the AA metabolism and potential therapies, we also introduce the current newly clinical studies targeting AA metabolisms in the different disease conditions....
2. Cellular metabolism in a nutshell 2.1. Glycolysis and the tricarboxylic acid cycle The term glycolysis describes a series of cytosolic enzymatic reactions that generate pyruvate from glucose. After being imported from the extracellular space by specialized transporters (such as Glut1), glucose is ...