Effect of newly synthesized progesteron derivatives on apoptotic and metastatic pathway in MCF-7 breast cancer cellsdoi:10.1093/annonc/mdw362.46S. YahyaM. AbdelhalimG. ElsayedA. OthmanAnnals of Oncology
Taken together, these studies emphasise the importance of the signal/leader peptide in the correct trafficking and processing of RPE proteins for secretion, so that physiological amounts are released outside the cell. Sign in to download hi-res image Fig. 2. Role of N-terminal leader sequence ...
Our results indicate that in addition to serving as a precursor for higher glycosylation in the Golgi, a major fraction of newly synthesized GlcCer is rapidly transported to the plasma membrane by a non-Golgi pathway and then rapidly turned over. 展开 ...
(A) Images of the haemogenic endothelium (HE) culture taken after 48 h in absence or presence of doxycycline (dox). The scale bar corresponds to 200 μm. (B) Flow cytometry analysis of VE-Cad and CD41 expression after 2 days of culture in absence or presence of dox. (C) Bar ...
By genome-wide association studies of 419 accessions of the upland cotton, Gossypium hirsutum, we identify ten loci that are associated with resistance against Verticillium wilt. Among these loci, SHZDI1/SHZDP2/AYDP1 from chromosome A10 is located on a fragment introgressed from Gossypium arboreum...
synthesis and degradation affects a pool of newly synthesized collagen, while maintaining the persistent collagen network. Disabling the circadian clock causes abnormal collagen fibrils and collagen accumulation, which are reduced in vitro by the NR1D1 and CRY1/2 agonists SR9009 and KL001, ...
In combinatorics, a hitting set of a collection of sets C, each taken from a universe of items U, is a set H ⊂ U that intersects every set in C. In this paper, we refer to a set H ⊂ N as a hitting set for a collection of vectors E ⊂ ℝnif H intersects the non...
For a long time, the functional significance of cGAS N-terminus (1 ~ 159) remains unclear [23]. However, researchers have recently taken a small step closer toward this. Du and Chen reported that N-terminus contributes to cGAS and DNA liquid droplets formation in physiological buffer and...
Taken together, we here show for the first time that a human mitosRNA functions in a miRNA-like fashion in CHO producer cells. By global transcriptome profiling of mitosRNA-1978 targets we designed a superior co-engineering approach involving gene silencing of two critical components within the ...
For the screen results, only samples with more than 50% of cells in the chosen gate were taken in to account. Median GFP intensity was calculated for the gated population in each sample. Treatment effects were measured as a difference between signal intensity of inhibitor and a non-stimulated...