摘要: Framing her own story of staggering loss and soaring hope with the biblical story of Job, Guthrie takes her fellow sufferers by the hand and guides them on a pathway through pain straight to the heart of God.出版时间: January 2007 ...
[37]. The Wnt pathway is a key player in the maintenance of somatic stem cells in a wide array of tissues and organs including the intestines, heart, blood, brain, and mammary gland [38]. Therefore, abnormal activation ofWnt signalinghas implicated in the regulation of many cancers, and ...
downstream signals can control the production of type I interferon and nuclear factor kappa-light-chain-enhancer of activated B cells to promote the activation of pro-inflammatory molecules, which are mainly induced during antiviral responses. However,...
As an evolutionarily conserved signalling network, the Hippo pathway plays a crucial role in the regulation of numerous biological processes. Thus, substantial efforts have been made to understand the upstream signals that influence the activity of the Hippo pathway, as well as its physiological functi...
In metastasis, cancer cells must prevent anoikis (apoptosis induced by detachment) and enter the blood vessels and should get out of it (intravasation and extravasation), thereby demonstrating complete metastatic colonization and drug resistance. These are critical features of cancer stem cells that ...
Molecular Mechanisms Underlying the Circadian Rhythm of Blood Pressure in Normotensive Subjects. Curr Hypertens Rep. 2020;22:50. Article CAS PubMed PubMed Central Google Scholar Atalay S, Jarocka-Karpowicz I, Skrzydlewska E. Antioxidative and anti-inflammatory properties of cannabidiol. Antioxidants....
Kuntz said he knows of a few practices that are large enough to develop their own pathways, such as Moffitt Cancer Center in Tampa, Florida, but he cautioned that the work “is not for the faint of heart.”“While the building (of pathways) is very, very challenging, the mainten...
These data demonstrate that C1ql1/Ctrp14 and C1ql4/Ctrp11 stimulate the new blood vessel growth by activation of ERK1/2 signal pathway. The proangiogenic activity of C1ql1/Ctrp14 and C1ql4/Ctrp11 provides novel insights into the new opportunities for therapeutic intervention by targeting C1QLs ...
Transcriptome analysis in combination with pathway-focused bioassays is suggested to be a helpful approach for gaining deeper insights into the complex mechanisms of action of herbal multicomponent preparations in living cells. The polyherbalism based concept of Tibetan and Ayurvedic medicine considers thera...
et al. The Tie receptor tyrosine kinase is expressed by human hematopoietic progenitor cells and by a subset of megakaryocytic cells. Blood 87, 2212–2220 (1996). CAS PubMed Google Scholar Hashiyama, M. et al. Predominant expression of a receptor tyrosine kinase, TIE, in hematopoietic stem...