eosinophilic cytoplasm, high N:C ratio, prominent nucleoli, conspicuous mitoses and necrosis. The thickened cords contain more than 6 - 10 cells thick tumor cells, consistent with macrotrabecular pattern. This pattern of hepatocellular carcinoma has been recently categorized...
Endometrial clear cell carcinoma (14%) (Am J Surg Pathol 2018;42:1596) Endometrial carcinosarcoma (26%) (Am J Surg Pathol 2018;42:1596) Gastrointestinal: Hepatocellular carcinoma (2%) (Hum Pathol 2003;34:994) Pancreatic adenocarcinoma (5%) (Hum Pathol 2003;34:994) ...
Yeo YH, Samaan JS, Ng WH, Ting P-S, Trivedi H, Vipani A et al (2023) Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma. Clin Mol Hepatol 29:721–732 Article PubMed PubMed Central Google Scholar Nisar S, Aslam M S. 2023 Is Ch...
This article outlines the pathway for the processing of liver tumour tissue in the histopathology laboratory, before discussing the pathological features of the more commonly encountered benign and malignant liver tumours. Included within this discussion are epithelial tumours of both hepatocellular and ...
HCC: Hepatocellular carcinoma; DN: Dysplastic nodule; HGDN: High grade dysplastic nodule; LGDN: Low grade dysplastic nodule; RN: Regenerating nodule ReferencesLaboratory Information System Leads Whole Slide Image Diagnosis: Integration Digital Pathology with Paperless Pathology Workflow Kyoungbun Lee1, Jinw...
In hepatocellular carcinoma,IGFALSis described as a tumour suppressor; however, its contribution to other cancers is not well delineated. This Review addresses the endocrine physiology and pathology of ALS, discusses the latest cell and proteomic studies that suggest emerging cellular roles for ALS and...
Peliotic change inhepatocellular carcinoma: background parenchyma clearly malignant (Oncol Lett 2010;1:17) Board review style question #1 A 45 year old man presents to the emergency department complaining of abdominal pain but collapses and dies before receiving care. Autopsy shows several findings, ...
possible lipid rich lesions, including angiomyolipoma, coelomic fat ectopia, diffuse steatosis, focal nodular hyperplasia, hepatic adenoma, lipoma and myelolipoma (Arch Pathol Lab Med 1985;109:783). Fatty change has also been reported in hepatocellular carcinoma (AJR Am J Roentgenol 1988;151:717)...
Between 10 and 20% of NAFLD progresses to non-alcoholic steatohepatitis (NASH), which can cause liver cirrhosis and can also lead to hepatocellular carcinoma. Liver macrophages are considered to be related to inflammation and fibrosis observed in NASH. This review outlines liver-derived signals ...
Hepatocellular carcinoma Cholangiocarcinoma Lung adenocarcinoma Kidney tumor Thyroid tumor Melanoma Undifferentiated pleomorphic sarcoma (UPS) Liposarcoma Angiosarcoma Sample pathology report Left lobe of liver, core biopsy: Poorly differentiated carcinoma, consistent with breast primary (see comment) ...