In contrast to most other malignancies, hepatocellular carcinoma (HCC), which accounts for approximately 90% of primary liver cancers, arises almost exclusively in the setting of chronic inflammation. Irrespective of etiology, a typical sequence of chron
The immunology of hepatocellular carcinoma. Nat Immunol. 2018:1.Ringelhan M, Pfister D, O'Connor T, Pikarsky E, Heikenwalder M. The immunology of hepatocellular carcinoma. Nat Immunol 2018; 19(3): 222-232Ringelhan M, Pfister D, O'Connor T, Pikarsky E, Heikenwalder M. The immunology...
The general relevance of the immune system for cancer development and therapy is increasingly recognized. However and although the immune contexture of most human cancer types has been determined, a global characterisation of the immune tumour microenvir
讲者:Sebastian Stintzing, MD | Medical Department, Division of Hematology, Oncology, and Cancer Immunology (CCM), Charité Universitätsmedizin Berlin 摘要号:3508 panitumumab在左半结肠肿瘤、MSS/MSI-L和RAS/BRAF WT患者的疗效:Ⅲ期 PARADIGM 试验的生物标志物研究 Efficacy of panitumumab in patients wit...
The immunology of hormone receptor positive breast cancer Front Immunol, 12 (2021), p. 674192 View in ScopusGoogle Scholar [5] J. Budczies, M. Bockmayr, C. Denkert, et al. Classical pathology and mutational load of breast cancer - integration of two worlds J Pathol Clin Res, 1 (4) ...
2024, Frontiers in Immunology ULK1 Depletion Protects Mice from Diethylnitrosamine-Induced Hepatocarcinogenesis by Promoting Apoptosis and Inhibiting Autophagy 2023, Journal of Hepatocellular Carcinoma The Immunoregulatory Effect of Aconite Treatment on H22 Tumor-Bearing Mice via Modulating Adaptive Immunity and...
Ovarian cancer cell line SKOV6 was a kind gift of Dr. Anil Suri (National Institute of Immunology, New Delhi). The human hepatoma cells Huh7 was a kind gift from Dr. A. Siddiqui (University of Colorado, Denver). The immortalized human hepatocytes (IHH) were kindly provided by Dr. F. ...
https://www.biologydiscussion.com/immunology/lymphoid-organs-primary-and-secondary-with-diagram/56268.png Primary Lymphoid Organs: In primary lymphoid organs, immature lymphocytes differentiate to mature ones into an antigen sensitive lymphocytes and after maturation, lymphocytes migrate to secondary lymphoid...
The immunology of hepatocellular carcinoma. Nat. Immunol. 19, 222–232 (2018). Article CAS PubMed Google Scholar Keenan, B. P., Fong, L. & Kelley, R. K. Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. J. Immunother....
Hepatocellular carcinoma (HCC) is a highly malignant tumor with significant global health implications. The role of CD4+ T cells, particularly conventional CD4+ T cells (Tconvs), in HCC progression remains unexplored. Furthermore, epigenetic factors are