passenger strand 的意思并非是将传统意义的passenger和strand 词义组合一起。它是医学上肿瘤学科里的一个专业用语,见“成熟miRNA链被称为引导链(guide strand),相对应的另一条链被称为过客链(passenger strand)”。---passenger ['pæsindʒə] 原义为:n. 乘客;旅客;过路人;[俚]碍手碍脚的人strand [...
RISC中的成熟miRNA链被称为引导链(guide strand),相对应的另一条链被称为过客链(passenger strand)。最小的RISC至少包 …zhidao.baidu.com|基于5个网页 2. 链中与靶序列相同那条 ...ced silence complex),此时,双链中与靶序列相同那条(passenger strand)被降解,与靶序列互补的一条(guide strande…wenwen.so...
RISC中的成熟miRNA链被称为引导链(guide strand)，相对应的另一条链被称为过客链(passenger strand)。最小的RISC至少包括下列物质：Argonaute (Ago) protein、Dicer以及TRBP，而RISC还可以和许多辅助蛋白相互作用[6]。一旦成熟miRNA的guide strand被装载进入RISC，它将会和其靶mRNA的 3’ UTR结合，从而...
Ago2 then cleaves the siRNA passenger strand, thereby liberating the single-stranded guide. For siRNAs, virtually all RISC is assembled through this cleavage-assisted mechanism. In contrast, passenger-strand cleavage is not important for the incorporation of miRNAs that derive from mismatched duplexes...
In miRNA biogenesis, passenger strands of miRNAs are degraded and have no biological activities in cells. The aims of this study were to investigate the functional significance of the passenger strand of miR‑145 and to identify miR‑145‑3p‑regulated oncogenic genes in HNSCC cells. ...
The processing of the pre-miRNA hairpin generates a miRNA duplex, which consists of a miRNA (guide strand) and a miRNA* (passenger strand). miR-31 is an oncogenic miRNA and is up-regulated in oral squamous cell carcinoma (OSCC). miR-31* shows a high level of conservation across species...
Interestingly, microRNA-27a passenger strand (also call microRNA-27a*) in infarcted cardiac tissues and extracellular exosomes shows a relatively high abundance which normally undergoes intracellular degradation (Figure. 1). However, the role of microRNA-27a* in the onset and progression of CHF ...
The miR-21* passenger strand expression in comparison with miR-21guide strand and pri-mir-21 transcript in mouse hearts, from 1 month to 24 months of age.Xiaomin, ZhangGohar, AzharJeanne, Y. Wei
Manual transmission for small passenger cars, urban buses and trucks, has planetary wheel set, which is arranged on shaft strand and has four shafts, of which three shafts are connected with shift collars respectively 来自 掌桥科研 喜欢 0 阅读量: 5 ...
A transverse running strand (8) made from high-tensile fibers such as glass fibers is integrated with the cross bar, where the strand is fixed at the fastening consoles. A plastic bumper outer shell (5) is provided for covering the cross bar. 展开 ...