Passenger strand miRNA miR-31* regulates the phenotypes of oral cancer cells by targeting RhoA. Oral Oncol. 2013, 49, 27-33. [CrossRef] [PubMed]Chang, K.W.; Kao, S.Y.; Wu, Y.H.; Tsai, M.M.; Tu, H.F.; Liu, C.J.; Lui, M.T.; Lin, S.C. Passenger strand miRNA miR-...
passenger strand 的意思并非是将传统意义的passenger和strand 词义组合一起。它是医学上肿瘤学科里的一个专业用语,见“成熟miRNA链被称为引导链(guide strand),相对应的另一条链被称为过客链(passenger strand)”。---passenger ['pæsindʒə] 原义为:n. 乘客;旅客;过路人;[俚]碍手碍脚的人strand [...
RISC中的成熟miRNA链被称为引导链(guide strand)，相对应的另一条链被称为过客链(passenger strand)。最小的RISC至少包括下列物质：Argonaute (Ago) protein、Dicer以及TRBP，而RISC还可以和许多辅助蛋白相互作用[6]。一旦成熟miRNA的guide strand被装载进入RISC，它将会和其靶mRNA的 3’ UTR结合，从而...
The processing of the pre-miRNA hairpin generates a miRNA duplex, which consists of a miRNA (guide strand) and a miRNA* (passenger strand). miR-31 is an oncogenic miRNA and is up-regulated in oral squamous cell carcinoma (OSCC). miR-31* shows a high level of conservation across species...
passenger strand 的意思并非是将传统意义的passenger和strand 词义组合一起.它是医学上肿瘤学科里的一个专业用语,见“成熟miRNA链被称为引导链(guide strand),相对应的另一条链被称为过客链(passenger strand)”.---passenger ['pæsindʒə] 原义为:n.乘客;旅客;过路人;[俚]碍手碍脚的人strand [str...
passenger strand 的意思并非是将传统意义的passenger和strand 词义组合一起.它是医学上肿瘤学科里的一个专业用语,见“成熟miRNA链被称为引导链(guide strand),相对应的另一条链被称为过客链(passenger strand)”.---passenger ['pæsindʒə] 原义为:n.乘客;旅客;过路人;[俚]碍手碍脚的人strand [str...
MiR-21-5p (guide strand) is a commonly upregulated miRNA in disease states, including cancer and drug resistance. However, the expression and function of miR-21-3p (passenger strand) are not well understood. We found that upregulation of miR-21-5p and miR-21-3p tune purine metabolism ...
RISC中的成熟miRNA链被称为引导链(guide strand),相对应的另一条链被称为过客链(passenger strand)。最小的RISC至少包 …zhidao.baidu.com|基于5个网页 2. 链中与靶序列相同那条 ...ced silence complex),此时,双链中与靶序列相同那条(passenger strand)被降解,与靶序列互补的一条(guide strande…wenwen.so...
Thus, we investigated a potential paracrine miRNA crosstalk between cardiac fibroblasts and cardiomyocytes and found that cardiac fibroblasts secrete miRNA-enriched exosomes. Surprisingly, evaluation of the miRNA content of cardiac fibroblast-derived exosomes revealed a relatively high abundance of many miRNA...
For each siRNA duplex, only one strand, the guide, is assembled into the active RISC; the other strand, the passenger, is destroyed. An ATP-dependent helicase has been proposed first to separate the two siRNA strands, then the resulting single-stranded guide is thought to bind Ago2. Here,...