Skip to main contentSkip to article Journals & Books Help Search My accountSign in View PDF Download full issue Search ScienceDirect Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Volume 1695, Issues 1–3, 29 November 2004, Pages 235-247...
ubiquitinUbFluorPARKIN is a RING-Between-RING (RBR) E3 ligase, which ubiquitinates mitochondrial proteins in response to mitochondrial damage. Ser65 of PARKIN is phosphorylated by kinase PINK1 (pPARKIN), which causes partial PARKIN activation. PINK1 also phosphorylates Ser65 of ubiquitin (pUb), ...
Mutations in the gene encoding for the E3 ubiquitin ligase Parkin are associated to a rare form of familiar autosomal recessive Parkinsonism. Despite decades of research on the Parkin protein, whose structure has been recently solved, little is known abo
英文名称:Recombinant Rat E3 ubiquitin-protein ligase parkin (Park2)Recombinant Rat E3 ubiquitin-protein ligase parkin (Park2) is available 1 time 来自 Mybiosource labs,中文名称:重组大鼠E3泛素蛋白连接酶parkin(Park2)重组大鼠E3泛
基因名全称parkin RBR E3 ubiquitin protein ligase 蛋白名全称E3 ubiquitin-protein ligase parkin 推荐稀释比 Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA re...
PRKN;AR-JP;LPRS2;PARK2;PDJ;parkin RBR E3 ubiquitin protein ligase;E3 ubiquitin-protein ligase parkin;Parkinson disease (autosomal recessive, juvenile) 2, parkin;parkinson juvenile disease protein 2;parkinson protein 2 E3 ubiquitin protein ligase;parkinson protein 2, E3 ubiquitin protein ligase (parki...
Mutations in the PTEN-induced kinase 1 (PINK1) and Parkin RBR E3 ubiquitin-protein ligase (PARKIN) genes are associated with familial forms of Parkinson’s disease (PD). PINK1, a protein kinase, and PARKIN, an E3 ubiquitin ligase, control the specific elimination of dysfunctional or superfluous...
Print datasheet MSDS ¥2200/100 μL Cat No.14060-1-AP 浓度:1000 ug/ml 库存:现货 Size 点击咨询在线客服 mouseWB See more citations
并对基于荣气虚滞理论立方的活血荣络方进行体内,体外实验研究,聚焦于PINK1编码磷酸酶和张力蛋白同源物诱导的假定激酶1(PTEN induced putative kinase 1,PINK1)/E3泛素连接酶Parkin(Parkin RBR E3 ubiquitin protein ligase)信号通路,探讨活血荣络方抗脑缺血再灌注损伤的可能机制.第一部分理论探讨本部分旨在通过结合中西...
Parkin is a RING-between-RING E3 ligase that functions in the covalent attachment of ubiquitin to specific substrates, and mutations in Parkin are linked to Parkinson’s disease, cancer and mycobacterial infection. The RING-between-RING family of E3 ligases are suggested to function with a canonic...