Effect of a pan-caspase inhibitor (zVAD-fmk) and a specific caspase-8 inhibitor (zIETD-fmk) on the induction of apoptosis by LBW242 (LBW) or TRAIL or both agents.Eleonora PetrucciLuca PasquiniManuela BernabeiErnestina Saul...
Z-VAD-FMK_Pan-Caspase抑制剂_187389-52-2_Apexbio产品说明书
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is a broad spectrum caspase inhibitor, provides a cost effective, non toxic, and highly specific means of apoptotic inhibition and provides new insight into the design of new inhibitors. [1] it is significantly more effective in preventing apoptosis than the widely used inhibitors, zvad-...
even at extremely high concentrations. the effective concentration of q-vd-oph may provide a unique reagent when trying to revive hard to propagate cell lines from liquid nitrogen. the addition of this inhibitor to thawed cells would give the cells adequate time to recover, even in the presence...
Modula- tion of radiochemoimmunotherapy-induced B16 melanoma cell death by the pan-caspase inhibitor zVAD-fmk induces anti-tumor immu- nity in a HMGB1-, nucleotide- and T-cell-dependent manner. Cell Death Dis 2015; 6:e1761; PMID:25973681; http://dx.doi.org/10.1038/ cddis.2015.129...
One prerequisite that radiotherapy (RT) and chemotherapy (CT) result in anti-tumor immune responses is triggering of immunogenic cell death forms such as necroptosis. The latter is inducible by inhibition of apoptosis with the pan-caspase inhibitor zVAD-