Single-Molecule Sequencing in Real Time (SMRT)—单分子实时测序方法Pacific Biosciences 创新性地提出的新测序方法。Pacific Biosciences 于2004年成立,最初是基于康奈尔大学的一项研究而起步。2010年纳斯达克上市。仪器设备1. PaciBioRS, 2010年发售, 仅售于有限的11个客户, 2011年商业发售。
Pacific biosciences small molecule real-time (SMRT) deep sequencing detects significant viral population structure in brain vs non-brain autopsy tissues from combined antiretroviral therapy (cART)-positive subjects - ScienceDirectS.L. LamersD.J. Nolan...
纵观第三代测序之 Pacific Biosciences 众所周知,天然的 DNA 复制本身就是一个非常高效且准确的过程.真核生物 DNA 复制的速度达几 十个核苷酸/秒.若能以这样的神速测序,那可比 Sanger 测序快了几万倍.然而,知易行难.如何在不 影响聚合酶活性的前提下实时观察 DNA 合成,这可是个棘手的问题.要知道,DNA 聚合酶...
There are four main companies developing these sequencing systems [50] and the first to become commercially available is the Single Molecular Real Time (SMRT) DNA sequencer from Pacific Biosciences, due to be released in late 2010 [51]. It is expected to produce read lengths up to 10 000 ba...
耗材部分包括SMRT Cell和试剂盒。PacBio RS上的每个反应消耗一个SMRT Cell。8个SMRT Cell包装成8Pac的形式。另外,他们还提供了三种试剂盒,用途各不同。Template Preparation Kit将DNA转化成SMRTbell文库形式。Binding Kit则将这个文库与聚合酶结合,为测序做准备。Sequencing Kit包含了实时测序所需的试剂。每个样本可在...
Pacific Biosciences of California Inc.(纳斯达克股票代码:PACB)是基因组,转录组和表观基因组的高质量测序的领先供应商,于4月24号宣布Sequel®II系统的商业发布。该系统包括新的8M SMRT®Cell,以及配套试剂,仪器控制软件和SMRT Link软件包。与之前的Sequel系统相比,新的系统进一步降低了测序项目的成本和时间,其通...
Illumina将以大约12亿美元的价格收购Pacific Biosciences,扩大对长读长序列测序并加速科学发现 汇集高度准确的短读长和长读长测序技术,为更完美的基因组视图铺平道路 Pacific Biosciences最新推出的Sequel SMRT®技术与Illumina的长期基础相结合,将更有助于生物发现和临床应用 ...
Pacific Biosciences市场发展部高级副总裁Kevin Corcoran说:“我们不断通过开发能够发挥我们系统独有特性的软件增强程序,持续改善PacBio RS的性能。 通过长序列读数、黄金标准精度及更高质量的拼接,基因组学团体可通过SMRT Sequencing获得真正的最终基因组。”
Pacific Biosciences of California, Inc. (Nasdaq:PACB) offers the PacBio(R) RS High Resolution Genetic Analyzer to help scientists solve genetically complex problems. Based on its novel Single Molecule, Real-Time (SMRT(R)) technology, the company's pro...
, Aug. 04, 2016 (GLOBE NEWSWIRE) — Pacific Biosciences of California, Inc. (Nasdaq:PACB) today announced it has released a set of key updates for the Sequel™ System, the company’s latest product based on its Single Molecule, Real-Time (SMRT®) Sequencing technology. The new ...