p53信号通路PCR基因芯片可以同时检测84个与p53信号通路相关的基因。这些基因包括参与细胞凋亡、细胞周期、细胞生长、增殖和分化以及DNA修复等过程的p53相关基因。利用实时定量PCR,研究者可以方便并且可信地对与p53信号通路相关的基因进行同时检测。 ProductSpeciesTechnologyCat. No.p53 Signaling Pathway PCR ArrayHumanGene ...
p53 signaling pathway polymorphisms,cancer risk and tumor phenotype in TP53 R337Hmutation carriers. Macedo GS,Vieira IA,Vianna FSL,et al. Familial Cancer . 2017Macedo GS, Vieira IA, Vianna FSL, et al. p53 signaling pathway polymorphisms, cancer risk and tumor phenotype in TP53 R337H mutation ...
p53 signaling helps maintain genome stability by preventing mutations. Use the interactive pathway map to find related RayBiotech products.
The p53 protein is known for performing essential functions in the maintenance of genomic stability in somatic cells and prevention of tumor formation. Studies of the p53 signaling pathway have suggested associations between some polymorphisms and infertility, post-in vitro fertilization implantation failure...
p53非依赖性信号通路在dna损伤致细胞凋亡中的研究进展 p53-independent signaling pathway in dna damage-induced cell apoptosis 下载积分: 2000 内容提示: 第42卷第2期浙江大学学报( 医学版)J ouRN AL oF zH EJ IAN G uN IVERsITY( M ED IcAL scIEN cEs)Vol 42N o 22013年20 1 3hnp:∥ w w w .j...
p53 signaling pathway polymorphisms, cancer risk and tumor phenotype in TP53 R337H mutation carriers 来自 国家科技图书文献中心 喜欢 0 阅读量: 58 作者: GS Macedo,IA Vieira,FSL Vianna,B Alemar,J Giacomazzi,APC Brandalize,M Caleffi,SM Volc,DCRG Henrique,EI Palmero 展开 摘要: Li-Fraumeni ...
BACKGROUND: The p53 signaling pathway may be important for the pathogenesis of emphysematous changes in the lungs of smokers. Polymorphism of p53 at codon 72 is known to affect apoptotic effector proteins, and the polymorphism of mouse double minute 2 homolog (MDM2) single nucleotide polymorphism ...
The sodium pump α1 subunit regulates bufalin sensitivity of human glioblastoma cells through the p53 signaling pathwayGliomaBufalinSodium pumpp53ApoptosisBufalin is the primary component of the traditional Chinese medicine "Chan Su," which has been widely used for cancer treatment at oncology clinics ...
Objective: To investigate the course of tubular cell senescence and expressions of p53, p21, and Rb during the late phase of ischemia/reperfusion (IRI) in the kidney, and assess the effects of the p53-Rb pathway on tubular cell senescence. Methods: Experimental models of unilateral renal ...
and the expressions of these inflammatory cytokine were negatively correlated to the expressions of p53.【Conclusion】 When A549 cells are infected with BCG,p53 would cooperate with p300 in the p53 signaling pathway to inhibit the activation of NF-κB,TLR-4 and TRAF6,and negatively regulate the ...