Bates S, Vousden KH: p53 in signaling checkpoint arrest or apoptosis. Curr Opin Genet Dev 1996; 6: 12-18. Harris CC, Hollstein M: Clinical implications of the p53 tumor-suppressor gene. N Engl J Med 1993; 329: 1318-1327. Linzer DI, Levine AJ: Characterization of 54k dalton celluar ...
Bengal E.The p38 MAPK signaling pathway: A major regulator of skeletal muscle development.Mol. Cel...
■ ALOX12 是 p53 介导的铁死亡途径必不可少的顾伟团队深入研究，于 2019 年在 Nature Cell Biology 上发表了“ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway”文章，指出 ALOX12 介导的、不依赖 ACSL4 的铁死亡途径对 p53 介导的肿瘤抑制作用非常重要。ALOX12 基...
p53信号通路PCR基因芯片可以同时检测84个与p53信号通路相关的基因。这些基因包括参与细胞凋亡、细胞周期、细胞生长、增殖和分化以及DNA修复等过程的p53相关基因。利用实时定量PCR,研究者可以方便并且可信地对与p53信号通路相关的基因进行同时检测。 ProductSpeciesTechnologyCat. No.p53 Signaling Pathway PCR ArrayHumanGene ...
The p53 protein is known for performing essential functions in the maintenance of genomic stability in somatic cells and prevention of tumor formation. Studies of the p53 signaling pathway have suggested associations between some polymorphisms and infertility, post-in vitro fertilization implantation failure...
p53 signaling helps maintain genome stability by preventing mutations. Use the interactive pathway map to find related RayBiotech products.
p53 can be used as apotential target for the prognosis and treatment of colorectal cancer.【Key words】 Colorectal cancer; p53; Murine double minute 2; Clinicopathological features;Signaling pathway; PrognosisDOI:10.3760/cma.j.issn.1673鄄4181.2019.01.005·论著·0 引 言结直肠癌是消化系统最常见的...
p53非依赖性信号通路在dna损伤致细胞凋亡中的研究进展 p53-independent signaling pathway in dna damage-induced cell apoptosis 下载积分:2000 内容提示: 第42卷第2期浙江大学学报( 医学版)J ouRN AL oF zH EJ IAN G uN IVERsITY( M ED IcAL scIEN cEs)Vol 42N o 22013年20 1 3hnp:∥ w w w .j ...
6. Chène P, Fuchs J, Bohn J, García-Echeverría C, Furet P, Fabbro D. A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines.J Mol Biol.2000;299(1):245-253. doi:10.1006/jmbi.2000.3738 ...