p53 signaling helps maintain genome stability by preventing mutations. Use the interactive pathway map to find related RayBiotech products.
p53信号通路PCR基因芯片可以同时检测84个与p53信号通路相关的基因。这些基因包括参与细胞凋亡、细胞周期、细胞生长、增殖和分化以及DNA修复等过程的p53相关基因。利用实时定量PCR,研究者可以方便并且可信地对与p53信号通路相关的基因进行同时检测。 ProductSpeciesTechnologyCat. No.p53 Signaling Pathway PCR ArrayHumanGene ...
■ ALOX12 是 p53 介导的铁死亡途径必不可少的顾伟团队深入研究，于 2019 年在 Nature Cell Biology 上发表了“ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway”文章，指出 ALOX12 介导的、不依赖 ACSL4 的铁死亡途径对 p53 介导的肿瘤抑制作用非常重要。ALOX12 基...
Bengal E.The p38 MAPK signaling pathway: A major regulator of skeletal muscle development.Mol. Cel...
CTLA4 Signaling Pathway Killer T Cell Mediated Apoptosis Pathway Cytokine Pathways | Growth Factor Pathways 细胞因子网络 ErbB 家族通路 Fas 通路 FGF 通路 Granulocyte Adhesion and Diapedesis 颗粒酶 A 和颗粒酶 B 信号通路 GSK3 信号...
The p53 protein is known for performing essential functions in the maintenance of genomic stability in somatic cells and prevention of tumor formation. Studies of the p53 signaling pathway have suggested associations between some polymorphisms and infertility, post-in vitro fertilization implantation failure...
p53 signaling pathway p53 protein activation mechanism Having a short half-life, p53 is normally maintained at low levels in unstressed mammalian cells by continuous ubiquitylation and subsequent degradation by the 26S proteasome. Nonphosphorylated p53 is...
Bates S, Vousden KH: p53 in signaling checkpoint arrest or apoptosis. Curr Opin Genet Dev 1996; 6: 12-18. Harris CC, Hollstein M: Clinical implications of the p53 tumor-suppressor gene. N Engl J Med 1993; 329: 1318-1327. Linzer DI, Levine AJ: Characterization of 54k dalton celluar ...
p53非依赖性信号通路在dna损伤致细胞凋亡中的研究进展 p53-independent signaling pathway in dna damage-induced cell apoptosis 下载积分: 2000 内容提示: 第42卷第2期浙江大学学报( 医学版)J ouRN AL oF zH EJ IAN G uN IVERsITY( M ED IcAL scIEN cEs)Vol 42N o 22013年20 1 3hnp:∥ w w w .j...
In this respect,p53 signaling pathway was found to be activated in response to cisplatin treat-ment in both EC109/CDDP and EC109,which may contribute to the cytotoxic effect of cisplatin.Key words cisplatin; p53; esophageal squamous carcinoma cellThis study was supported by the National Natural ...