According to another previous study, PELP1 could enhance the phosphorylation of GSK3β and further activate beta-catenin signaling [42]. So we conclude that CARM1 may interact with PELP1 to activate pGSK3β/β-catenin signaling pathway. Secondly, PRMT1 could methylate Axin to enhance the ...
p-GSK3 beta 抗体 2D3 是小鼠单克隆 IgG1,在11篇文献中引用,提供 50 µg/0.5 ml 针对磷酸化肽段,与GSK-3β的丝氨酸9周围的氨基酸残基对应,human来源 推荐用于 mouse, rat 和 human 来源的Ser 9 phosphorylated GSK-3β WB 和 IP检测 目前,我们还没有完成p-GSK3 beta 抗体 (2D3)的首选二抗检测试剂...
Ghrelin has been shown to alleviate neuropathic pain by inhibiting the release of proinflammatory cytokines. The purpose of this study was to investigate the role of GSK-3β/β-catenin signaling in mediating the effect of ghrelin on neuropathic pain and
Xing XS, Liu F, He ZY (2015) Akt regulates beta-catenin in a rat model of focal cerebral ischemia-reperfusion injury. Mol Med Rep 11:3122–3128 CAS PubMed Google Scholar Liu H, Ou S, Xiao X et al (2015) Diabetes worsens ischemia–reperfusion brain injury in rats through GSK-3beta...
英文名称:ELISA Kit for Glycogen SynthaHZ KinaHZ 3 Beta (GSK3b) 分子式:电询 纯度:99 % 产地:中国/美国/德国 品牌:BioLegend,Cygnus,IBL,TSZ等国内外品牌 包装规格:96T/48T 货号:xyD317Ra 别名:电询 大鼠糖原合酶激酶3β(GSK3β)检测试剂盒酶联免疫吸附试验(ELISA)因其操作简单,灵敏度高,特异性好,...
Beta-catenin is involved in both cell-cell adhesion and in transcriptional regulation by the Wingless/Wnt signalling pathway. Alterations of components of ... K Rask,A Nilsson,Br?nnstr?m, M,... - 《British Journal of Cancer》 被引量: 2148发表: 2003年 GSK-3 is essential in the pathogene...
(LiCl, SB-415286, and AR-A014418). Using a migrationassay kit, we found that the motility of hBM-MSCs wassignificantly enhanced by GSK-3β inhibition. Western blotanalysis revealed increased levels of migration-related signal-ing proteins such as phospho-GSK-3β, β-catenin, phospho-c-Raf,...
有研究表明,GSK3β磷酸化失活可激活Wnt信号通路,通过维持β-catenin的稳定促进肿瘤细胞的恶性转化[12-13]。 综上所述,在宫颈癌发展过程中GSK3β蛋白表达及活性逐渐降低,提示GSK3β基因可能在宫颈癌组织中为抑癌基因,但GSK3β基因及其磷酸化水平在宫颈癌发生发展中的具体机制还有待进一步深入研究探讨。 [1]胡...
异常聚集的β-catenin进入核内,与T细胞因子/白细胞移动增强因子结合,启动下游靶基因的表达。在Wnt信号传导通路中,GSK-3β是负性调节因素,β-catenin是正性调节因素,且GSK-3β是决定β-catenin磷酸化的关键激酶。对GSK-3β的抑制能使β-catenin不被磷酸化而降解,从而使β-catenin核聚集,抑制凋亡发生,促进肿瘤细胞...
According to another previous study, PELP1 could enhance the phosphorylation of GSK3β and further activate beta-catenin signaling [42]. So we conclude that CARM1 may interact with PELP1 to activate pGSK3β/β-catenin signaling pathway. Secondly, PRMT1 could methylate Axin to enhance the ...