Outer membrane vesicles (OMVs) are spontaneously released by many gram-negative bacteria during their growth and constitute an important virulence factor for bacteria, helping them to survive through harsh environmental conditions. Native OMVs, naturally-released from bacteria, are produced at a level to...
Outer membrane vesicles (OMVs) produced by Gram-negative bacteria exhibit enormous functional diversity depending on the bacterial species and environmental niche: these have enabled various physiological roles for these vesicles to play and at the same time OMVs have found important medical applications....
In numerous studies, bacterial outer membrane vesicles (OMVs) have proved attractive as vaccine platform for homologous bacterial strains, but also as antigen delivery platform for heterologous antigens of nonbacterial diseases, including viruses, parasites, and cancer. Their application has also been ...
This study investigated the production of outer membrane vesicles (OMVs) by B. cepacia cultured with sub-minimum inhibitory concentrations (MICs) of antibiotics and examined their pathogenic roles both in vitro and in vivo. B. cepacia ATCC 25416 produced more OMVs under antibiotic stress conditions ...
Extracellular vesicles (EVs) have been recognized as a universal method of cellular communications and are reportedly produced in bacteria, archaea, and eukaryotes. Bacterial EVs are often called “Outer Membrane Vesicles” (OMVs) as they were the result of a controlled blebbing of the outer membra...
Keywords: outer membrane vesicles (OMV); vaccines; adjuvants 1. Introduction OMVs are outer membrane vesicles of gram-negative bacteria, having stellar intrinsic immunostimulatory properties; they are nano-sized particles having a mean size between 20 to 200 nm; they are spherical buds of the outer...
Outer membrane vesicles (OMVs) are lipid-membrane-bounded nanoparticles that are released from Gram-negative bacteria via vesiculation of the outer membrane. They have vital roles in different biological processes and recently, they have received increas
we construct a versatile nanosystem that can not only inhibit the efferocytosis but also boost the following antitumor immunity. MerTK inhibitor UNC2025 is loaded into the bacterial outer membrane vesicles (OMVs), which are then modified with maleimide (mU@OMVs). The prepared mU@OMVs effectively ...
12. Bacterial outer membrane vesicles (OMVs), also known as extracellular vesicles, are naturally produced from all Gram-negative bacteria and have nano-sized lipid-bilayered vesicular structures composed of various immunostimulatory components13,14,15,16. This acellular bacterial OMV is one of the ...
membrane vesicles from Gram-negative bacteria into outer-inner membrane vesicles (OIMVs), explosive outer- membrane vesicles (EOMVs), and traditional OMVs according to their formation routes, structures, and compositions, which extended the scope of the bacterial membrane vesicles. In addition, the ...