载药细菌外膜囊泡(Outer Membrane Vesicles, OMV),细菌外囊泡是具有双层脂膜结构的大小为20-400 nm的球形囊泡,包含多种细菌来源的成分,且具备细菌的可修饰性和靶向性特点,是一种装载量巨大的药物载体。与此同时,细菌外囊泡不具备细菌的繁殖能力,相比细菌更为安全。因
Outer membrane vesicles (blebs) are produced by Escherichia coli, Salmonella, and all other gram-negative bacteria both in vitro and in vivo. Most of the research in the field has focused on the properties of vesicles derived from pathogenic bacteria and their interactions with eukaryotic cells. ...
Bacterial EVs are often called “Outer Membrane Vesicles” (OMVs) as they were the result of a controlled blebbing of the outer membrane of gram-negative bacteria such as Porphyromonas gingivalis (P. gingivalis). Bacterial EVs are natural messengers, implicated in intra- and inter-species cell-...
Anchoring fusion proteins with special functions on bacterial outer membrane vesicles can achieve multiple purposes such as targeted protein transport, fluorescent molecular labeling, and tumor treatment. It can be achieved by anchoring the fusion proteins on the OMV membranes-associated protein through gen...
Outer-membrane vesicles (OMVs) are spherical buds of the outer membrane filled with periplasmic content and are commonly produced by Gram-negative bacteria. The production of OMVs allows bacteria to interact with their environment, and OMVs have been found to mediate diverse functions, including promo...
Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions Nat. Rev. Microbiol, 13 (2015), pp. 605-619 CrossrefView in ScopusGoogle Scholar 15. Weiss A.A., Falkow S. Transposon insertion and subsequent donor formation promoted by Tn501 in Bordetella pertussis J. Bacteriol, ...
Outer membrane vesicles (OMVs) are released spontaneously during growth by many Gram‐negative bacteria. They present a range of surface antigens in a native conformation and have natural properties like immunogenicity, self‐adjuvation and uptake by immune cells which make them attractive for applicat...
Outer membrane vesiclesExtracellular vesiclesVaccine platformBioengineeringNanobiotechnologyOuter membrane vesicles (OMVs) are naturally non-replicating, highly immunogeni... E Eftychiou,N Brown,W Cheung,... - Asgct Meeting 被引量: 0发表: 2020年 Outer-membrane vesicles from Gram-negative bacteria: Bioge...
Figure 1. Outer Membrane Vesicles from Bacteroides fragilis Contain PSA (A) Transmission electron microscopy of electron-dense layer (EDL)-enriched B. fragilis (WT-OMV) and B. fragilisΔPSA (ΔPSA-OMV) reveals vesicles budding from the bacterial surface. (B) Immunoblot analysis of whole-cell ...