Previous studies suggested that OTUB1 (OTU domain-containing ubiquitin aldehyde-binding protein 1) serves as regulator of gene ubiquitination and participates in the pathogenesis of multiple malignancies. Therefore, to discover its molecular mechanism in CRC tumor growth and metastasis will contribute in ...
迄今为止,去泛素化酶OTUB1(OTU domain-containing ubiquitin aldehyde-binding proteins Otubain1)被发现与肿瘤的发生发展、神经退行性疾病、炎症、免疫和器官发育等关系密切[4] ,然而OTUB1在骨稳态维持中的功能及调控机制尚不清晰。 2023年4月7日,军事科学院军事医学研究院、国家蛋白质科学中心(北京)张令强团队与中国...
全称 OTU domain containing 6B 别名 计算分子量 293 aa, 34 kDa GenBank蛋白编号 BC029760 基因名称 OTUD6B Gene ID (NCBI) 51633 偶联类型 Unconjugated 形式 Liquid 纯化方式 Protein G Magarose purification UNIPROT ID Q8N6M0 储存缓冲液 PBS only , pH 7.3 储存条件 Store at -80°C. The prod...
迄今为止,去泛素化酶OTUB1(OTU domain-containing ubiquitin aldehyde-binding proteins Otubain1)被发现与肿瘤的发生发展、神经退行性疾病、炎症、免疫和器官发育等关系密切【4】,然而OTUB1在骨稳态维持中的功能及调控机制尚不清晰。 近日,军事科学院...
迄今为止,去泛素化酶OTUB1(OTU domain-containing ubiquitin aldehyde-binding proteins Otubain1)被发现与肿瘤的发生发展、神经退行性疾病、炎症、免疫和器官发育等关系密切[4] ,然而OTUB1在骨稳态维持中的功能及调控机制尚不清晰。 更多资讯: 2023年4月7日,军事科学院军事医学研究院、国家蛋白质科学中心(北京)...
蛋白别名:DUBA-7; OTU domain containing 1; OTU domain-containing protein 1 基因别名:DUBA7; OTDC1; OTUD1 UniProt ID:(Human) Q5VV17 Entrez Gene ID:(Human) 220213 功能 thiol-dependent ubiquitin-specific protease activitycysteine protease
目前,研究发现能够促进PTEN泛素化(包括单泛 素化与多聚泛素化)的泛素连接酶已有5个[Nedd4- 1(Neural precursor cell-expressed developmentally downregulated gene 4-1)、XIAP(X-chromosomelinked inhibitor of apoptosis protein)、WWP2(WW domain-containing protein 2)、CHIP(C terminus of Hsc70-interacting protei...
A putative OTU domain-containing protein 1 deubiquitinating enzyme is differentially expressed in thyroid cancer and identifies less-aggressive tumours. Br J Cancer. 2014;111:551–8. Article CAS PubMed Google Scholar Mevissen TE, Hospenthal MK, Geurink PP, Elliott PR, Akutsu M, Arnaudo N, et...
Gene Name OTU domain containing 7B Gene Symbol Otud7b Synonyms Za20d1; CEZANNE; Trabid2; 2900060B22Rik; 4930463P07Rik Organism Mouse Gene ID 229603 UniProt ID B2RUR8 Main Accession No. NM_001025613 Other Accession No. NM_001025613, NM_001025614, NM_001025613.1, NM_001025614.1, BC141397, ...
Ubiquitin thioesterase OTUB1, Otubain-1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Ubiquitin-specific-processing protease OTUB1, Deubiquitinating enzyme OTUB1, OTUB1, OTB1, OTU1, HSPC263, MGC4584, FLJ20113, FLJ40710, MGC111158. ...