^https://doi.org/10.1096/fj.201902610R ^Calvi LM. Osteolineage cells and regulation of the h...
参考 ^Asada, N., Katayama, Y. Regulation of hematopoiesis in endosteal microenvironments. Int J Hematol 99, 679–684 (2014). https://doi.org/10.1007/s12185-014-1583-1 ^https://doi.org/10.1096/fj.201902610R ^Calvi LM. Osteolineage cells and regulation of the hematopoietic stem cell....
Osteo-lineage cellOsteoporosisThe bone marrow microenvironment contains heterogeneous stromal cells, which are critical for bone remodeling and provide essential supportive roles for hematopoietic functions. Although the diversity of PDGFR伪+尾+mesenchymal stromal/stem cells (MSCs) get consensus, the osteo-...
Over the last 10 years, progress has been made in understanding the relationship between hematopoietic stem cells and their microenvironment, or niche. Increased knowledge of the microenvironment and its effects on hematopoiesis and leukemogenesis based on murine models may lead to the identification of...
Differential contribution of osteoclast- and osteoblast-lineage cells to CpG-oligodeoxynucleotide (CpG-ODN) modulation of osteoclastogenesis. J. Bone Miner. Res. 2005, 20, 1692-1699.Amcheslavsky A, Hemmi H, Akira S, Bar-Shavit Z 2005 Dif- ferential contribution of osteoclast- and osteoblast-...
1 HSC maintenance and expansion are thought to be regulated by interactions with bone marrow (BM) stromal elements, including osteoblasts2, 3, 4 and vascular endothelial cells,5 both of which have been proposed to form a supportive HSC “niche.”2,6, 7, 8 Osteoblasts, in particular, have ...
Haematopoietic stem cells (HSCs) can differentiate into cells of all lineages in the blood. However, the mechanisms by which cytokines in the blood affect HSC homeostasis remain largely unknown. Here we show that leukocyte cell-derived chemotaxin 2 (LECT
Acute Myeloid Leukemia (AML) alters the composition of the supportive bone marrow (BM) stroma, leading to a leukemia-supportive microenvironment that promotes extrinsic chemotherapy resistance. We previously reported functional and gene expression changes in patient derived mesenchymal stem cells (MSC) ...
macrophages and osteolineage cells Xin-Jiang Lu1, Qiang Chen1, Ye-Jing Rong1, Guan-Jun Yang1, Chang-Hong Li1, Ning-Yi Xu2, Chao-Hui Yu3, Hui-Ying Wang4, Shun Zhang5, Yu-Hong Shi1 & Jiong Chen1 Haematopoietic stem cells (HSCs) can differentiate into cells of all lineages in the ...
Osteolineage niche cells initiate hematopoietic stem cell mobilization Recent studies have implicated bone-lining osteoblasts as important regulators of hematopoietic stem cell (HSC) self-renewal and differentiation; however, ... SR Mayack,AJ Wagers - 《Blood》 被引量: 247发表: 2008年 Regulation of...