Although most of these RNA structures participate in viral replication, the functions of RNA structures in the genomic RNA of CoV in viral replication remain unclear. In this study, we investigated the functions of the higher-order RNA stem-loop (SL) structures SL5B, SL5C, and SL5D in the...
Two samples are collected from each patient: one for combination in the pool (the “pool” sample) and one for deconvolution if the pool tests positive (the “archive” sample)4. Both samples are placed into separate vials of transport media (Viral Transport Media, Universal Transport Media, ...
Since these patients do not seek medical evaluation, they will not detected by acute care tests (viral loads in PCR based assays). However such patients, may be detected after the fact by looking for evidence of past infection, in the form of circulating antibodies in the patients’ serum. ...
In a first example, two amino acid sequences are input (steps 1, 2) to an iterative procedure (steps 4-6). A frame size is selected in terms of a number of sequence elements. The procedure then compares pairs of frames, one from each sequence, to identify intramolecular and ...
RNA-binding RS repeat sequences can also be found in viral proteins, such as the nucleocapsid of severe acute respiratory syndrome coronavirus (SARS-CoV), causative agent of the alike-named disease. This protein employs RS-rich disordered region, in cooperation with other RNA-binding regions, to...
[1]. Both honey production and pollination services require strong, healthy colonies, which are threatened by a range of factors, but most significantly by disease. One of the major viral pathogens of honey bees is Deformed wing virus (DWV). When transmitted by the parasitic miteVarroa ...
been correlated with higher caspase expression shortly before and after pupation [9]. Among the different protective measures triggered by the insect immune system to thwart pathogen infection, host cell suicide through apoptosis can significantly reduce viral replication, dissemination and infectivity [10...
. 2010. RNA higher-order structures within the coronavirus 5' and 3' untranslated regions and there roles in viral replication. Springer-Verlag, Berlin.Liu P, Leibowitz J. Lal SK. RNA higher-order structures within the coronavirus 5′ and 3′ untranslated regions and their roles in viral ...
In eukaryotes, unlike in bacteria, gene order has typically been assumed to be random. However, the first statistically rigorous analyses of complete genomes, together with the availability of abundant gene-expression data, have forced a paradigm shift: in every complete eukaryotic genome that has ...