This six subunit complex (including Rap1 and Abf1 silencers) is required before DNA replication can begin in the eukaryotic cell. The N-terminal domain of Orc1 protein (the largest subunit) interacts with Sir1 and Sir1 mediates the recruitment of the other Sir proteins. Sir2 is a NAD-...
英文缩写 ORC 英文缩写ORC 英文全称origin recognition complex 中文解释起始点蛋白复合体 缩写简介 在DNA复制过程中识别其实保守序列的蛋白复合物。 其它解释 ORC(本地收货费用(广东省收取)) ORC(运筹学中心 ([美] California大学))
origin recognition complex ORC的意思 ORC 英文缩写ORC 英文全称origin recognition complex 中文解释起始点蛋白复合体 缩写分类生物科学 缩写简介在DNA复制过程中识别其实保守序列的蛋白复合物。
a复制起始位点识别复合物(ORC)由六个异源亚基组成,是调控DNA复制起始的关键蛋白。已有研究表明ORC在基因转录沉默、姐妹染色体粘连、细胞周期调控等细胞过程中也起着重要作用,而ORC的分子尚有不少分子机理有待解析,真核ORC的结构解析也因此成为许多生物学家努力的目标。本文为ORC的结构解析做了许多奠基性工作。首先,本文...
The origin recognition complex (ORC) is an essential component of the pre-replicative complex (pre-RC) that binds to replication origins for licensing. Levels of the largest ORC subunit, ORC1, oscillate during the mitotic cell cycle and regulate origin usage. In Drosophila, ORC1 levels increase...
Open Access The ORC/Cdc6/MCM2–7 complex, a new power player for regulated helicase loading Riera A, Fernandez-Cid A, Speck C (2013) The ORC/Cdc6/ MCM2-7 complex, a new power player for regulated heli- case loading... MS Charpentier,KM Dorr,FL Conlon 被引量: 7发表: 2013年 A ...
The Origin Recognition Complex (ORC) is essential for replication, heterochromatin formation, telomere maintenance and genome stability in eukaryotes. Here we present the structure of the yeast Orc1 BAH domain bound to the nucleosome core particle. Our d
人ORC6重组蛋白 ORC6L Origin recognition complex subunit 6 瑾萱生物 更新时间:2024年07月28日 家装建材,一站式购齐,点击查看更多优质好物! 价格 ￥888.00 起订量 1支起批 货源所属商家已经过真实性核验 物流 湖北 武汉 至全国全国包邮 大小规格/种属齐全 20ug 888.00元 8888支可售 1支888.00元...
A multi-subunit complex of proteins containing known ORC subunits has been identified in Drosophila, Xenopus, and humans, although all components have not been demonstrated to be homologs of yeast ORC. InXenopus, antibody-mediated depletion of ORC inhibits initiation of DNA replication (17, 18, ...
The location of origins of DNA replication within the Saccharomyces cerevisiae genome is primarily determined by the origin recognition complex (ORC) interacting with specific DNA sequences. The analogous situation in vertebrate cells is far less clear, although ORC subunits have been identified in ...