4.1The Operon Model of Gene Regulation Anoperonis a cluster of genes that are transcribed together to give a single messengerRNA(mRNA) molecule, which therefore encodes multiple proteins (Fig. 16.11). Suchpolycistronic mRNAis typically found inprokaryotes. The genes in an operon are often related...
4.1 The Operon Model of Gene Regulation An operon is a cluster of genes that are transcribed together to give a single messenger RNA (mRNA) molecule, which therefore encodes multiple proteins (Fig. 16.11). Such polycistronic mRNA is typically found in prokaryotes. The genes in an operon are ...
Model of the operon and its relation to the regulator gene. The promoter is controlled by variousregulatory elements that respond to environmental cues. One common method of regulation is carried out by a regulator protein that binds to theoperator region, which is another short segment of DNA f...
A mathematical model for genetic regulation of the lactose operon. In: Gervasi, O., Gavrilova, M. L., Kumar, V., Lagana, A., Lee, H. P., Mun, Y., Taniar, D., Tan, C. J. K. (Eds.), Lecture Notes in Computer Science. Vol. 3841. Springer....
The operon model has been the paradigm for understanding gene regulation and has laid a foundation for the development of modern molecular biology. In 1941, experiments by Jacques Monod showed that bacterial colonies of Escherichia grown in the presence of glucose and lactose metabolized glucose until...
gene. The same process allows some A gene product to also be made. Mutations that define the Lac-Operon model: Jacob and Monod found mutants that did not show the normal regulation, that is, synthesis of Z, Y, and A proteins only when lactose was present. ...
The regulatory model provides several potential explanations for the existence of operons [15]. It has been argued that co-regulation could be evolved more easily by modifying two independent promoters than by placing two genes in proximity [10]. A counter-argument to this is that, for complex...
Here we suggest that separation is due to benefits made possible by differential regulation of each operon. We present a simple mathematical model for the optimal distribution of genes into operons based on a balance of the cost of operons and the benefit of regulation that provides 'just-when...
The results showed that, in general, the genetic algorithm could explore the search space more effectively, obtaining networks with more edges than particle swarm optimization, thus allowing it to find networks satisfying the biological restriction of the model inferred. 展开 ...
Give an example of an inducible operon, describe the overall function of the gene(s) it encodes, and how it is regulated. How is an operon typically organized? Describe a type What is an operon, and what are the elements of the operon model? What is an operon composed of? The lac ...